Characteristics and molecular mechanisms through which SGLT2 inhibitors improve metabolic diseases: A mechanism review.
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DOI: 10.1016/j.lfs.2022.120543
Abstract: Metabolic diseases, such as diabetes, gout and hyperlipidemia are global health challenges. Among them, diabetes has been extensively investigated. Type 2 diabetes mellitus (T2DM), which is characterized by hyperglycemia, is a complex metabolic disease that… read more here.
Keywords: inhibitors improve; metabolic diseases; molecular mechanisms; mechanisms sglt2 ... See more keywords
An Overview of the Cardiorenal Protective Mechanisms of SGLT2 Inhibitors
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DOI: 10.3390/ijms23073651
Abstract: Sodium-glucose co-transporter 2 (SGLT2) inhibitors block glucose reabsorption in the renal proximal tubule, an insulin-independent mechanism that plays a critical role in glycemic regulation in diabetes. In addition to their glucose-lowering effects, SGLT2 inhibitors prevent… read more here.
Keywords: protective mechanisms; overview cardiorenal; mechanisms sglt2; cardiorenal protective ... See more keywords