The mechanisms of sorafenib resistance in hepatocellular carcinoma: theoretical basis and therapeutic aspects
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DOI: 10.1038/s41392-020-0187-x
Abstract: Sorafenib is a multikinase inhibitor capable of facilitating apoptosis, mitigating angiogenesis and suppressing tumor cell proliferation. In late-stage hepatocellular carcinoma (HCC), sorafenib is currently an effective first-line therapy. Unfortunately, the development of drug resistance to… read more here.
Keywords: hepatocellular carcinoma; mechanisms sorafenib; resistance; sorafenib resistance ... See more keywords