Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19115-y
Abstract: Telomerase is a specialized reverse transcriptase that adds GGTTAG repeats to chromosome ends and is upregulated in most human cancers to enable limitless proliferation. Here, we uncover two distinct mechanisms by which naturally occurring oxidized… read more here.
Keywords: mechanisms telomerase; telomerase; telomerase inhibition; therapeutic dntps ... See more keywords