Novel αO-conotoxin GeXIVA[1,2] Nonaddictive Analgesic with Pharmacokinetic Modelling-Based Mechanistic Assessment
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DOI: 10.3390/pharmaceutics14091789
Abstract: αO-conotoxin GeXIVA[1,2] was isolated in our laboratory from Conus generalis, a snail native to the South China Sea, and is a novel, nonaddictive, intramuscularly administered analgesic targeting the α9α10 nicotinic acetylcholine receptor (nAChR) with an… read more here.
Keywords: pharmacokinetic modelling; conotoxin; conotoxin gexiva; mechanistic assessment ... See more keywords