NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients
Sign Up to like & getrecommendations! Published in 2019 at "NPJ Breast Cancer"
DOI: 10.1038/s41523-019-0106-x
Abstract: The risk of developing metastatic disease in breast cancer patients is traditionally predictable based on the number of positive axillary lymph nodes, complemented with additional clinicopathological factors. However, since lymph node-negative patients have a 20–30%… read more here.
Keywords: mechanistic biomarker; breast; disease; breast cancer ... See more keywords
Mechanistic and Biomarker Studies to Demonstrate Immune Tolerance in Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.787498
Abstract: The induction of specific immunological tolerance represents an important therapeutic goal for multiple sclerosis and other autoimmune diseases. Sound knowledge of the target antigens, the underlying pathomechanisms of the disease and the presumed mechanisms of… read more here.
Keywords: mechanistic biomarker; immune tolerance; tolerance inducing; tolerance ... See more keywords