Structural Simplicity and Mechanistic Complexity in the Hammerhead Ribozyme.
Sign Up to like & getrecommendations! Published in 2018 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2018.07.006
Abstract: Natural or full-length hammerhead ribozymes are up to 1000-fold more active than their minimal counterparts that lack a complex tertiary interaction that pre-organizes and stabilizes the ribozyme active site, positioning RNA functional groups to facilitate… read more here.
Keywords: hammerhead; hammerhead ribozyme; mechanistic complexity; structural simplicity ... See more keywords
Mechanistic Complexity of Asymmetric Transfer Hydrogenation with Simple Mn–Diamine Catalysts
Sign Up to like & getrecommendations! Published in 2019 at "Organometallics"
DOI: 10.1021/acs.organomet.9b00457
Abstract: The catalytic asymmetric transfer hydrogenation (ATH) of ketones is a powerful methodology for the practical and efficient installation of chiral centers. Herein, we describe the synthesis, characterization, and catalytic application of a series of manganese… read more here.
Keywords: mechanistic complexity; diamine; asymmetric transfer; transfer hydrogenation ... See more keywords