Structural and mechanistic elucidation of inflammasome signaling by cryo-EM.
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DOI: 10.1016/j.sbi.2019.03.033
Abstract: The innate immune system forms an evolutionarily ancient line of defense against invading pathogens and endogenous danger signals. Within certain cells of innate immunity, including epithelial cells and macrophages, intricate molecular machineries named inflammasomes sense… read more here.
Keywords: elucidation inflammasome; mechanistic elucidation; inflammasome signaling; structural mechanistic ... See more keywords