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   Articles with "mechanistic insights" as a keyword



Mechanistic insights into the ROS-mediated inactivation of human aldehyde oxidase.

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recommendations! Published in 2023 at "FEBS letters"

DOI: 10.1002/1873-3468.14669

Abstract: Human aldehyde oxidase (hAOX1) is a molybdoenzyme that oxidizes aldehydes and N-heterocyclic compounds, thereby generating hydrogen peroxide (H2 O2 ) and superoxide during turnover. hAOX1 has been shown previously to be inactivated under turnover conditions… read more here.

Keywords: aldehyde oxidase; insights ros; ros mediated; human aldehyde ... See more keywords

New Mechanistic Insights into Persistent Luminescence in Rare‐Earth Co‐Doped Phosphate Phosphors

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recommendations! Published in 2025 at "Advanced Optical Materials"

DOI: 10.1002/adom.202502250

Abstract: Persistent phosphors, which exhibit prolonged luminescence after the cessation of excitation, hold considerable potential for a wide range of applications. However, the fundamental mechanisms governing persistent luminescence (PersL) are not yet fully understood. In this… read more here.

Keywords: mechanistic insights; luminescence; new mechanistic; persistent luminescence ... See more keywords

Mechanistic Insights and Rational Design of a Versatile Surface with Cells/Bacteria Recognition Capability via Orientated Fusion Peptides

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recommendations! Published in 2019 at "Advanced Science"

DOI: 10.1002/advs.201801827

Abstract: Abstract Hospital‐acquired infection causes many deaths worldwide and calls for the urgent need for antibacterial biomaterials used in clinic that can selectively kill harmful bacteria. The present study rationally designs fusion peptides capable of undergoing… read more here.

Keywords: smart surface; surface; recognition; fusion peptides ... See more keywords

Mechanistic insights and implications of FOXO‐SNAI interplay

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recommendations! Published in 2022 at "BioEssays"

DOI: 10.1002/bies.202200070

Abstract: Autophagy promotes both health and disease, depending on tissue types and genetic contexts, yet the regulatory mechanism remain incompletely understood. Our recent publication has uncovered a coherent FOXO‐SNAI feed‐forward loop in autophagy, which is evolutionarily… read more here.

Keywords: foxo snai; implications foxo; snai interplay; insights implications ... See more keywords
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Mechanistic Insights into the Activities of Major Families of Enzymes in Bacterial Peptidoglycan Assembly and Breakdown

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recommendations! Published in 2023 at "ChemBioChem"

DOI: 10.1002/cbic.202200693

Abstract: Serving as an exoskeletal scaffold, peptidoglycan is a polymeric macromolecule that is essential and conserved across all bacteria, yet is absent in mammalian cells; this has made bacterial peptidoglycan a well‐established excellent antibiotic target. In… read more here.

Keywords: activities major; bacterial peptidoglycan; assembly breakdown; peptidoglycan assembly ... See more keywords

Mechanistic Insights into Manganese (I)‐Catalyzed Chemoselective Hydroarylations of Alkynes: A Theoretical Study

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recommendations! Published in 2018 at "ChemCatChem"

DOI: 10.1002/cctc.201801301

Abstract: Density functional theory calculations were employed to elucidate the mechanism of Mn‐catalyzed chemoselective hydroarylation reactions. The Mn‐catalyzed [4+2] annulation undergoes a reaction pathway involving sequential imine‐directed C−H bond cleavage, alkyne insertion into the Mn−C bond,… read more here.

Keywords: catalyzed chemoselective; manganese catalyzed; study; alkyne insertion ... See more keywords

Mechanistic Insights for Nitromethane Activation into Reactive Nitrogenating Reagents

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recommendations! Published in 2021 at "ChemCatChem"

DOI: 10.1002/cctc.202100086

Abstract: Recently, it was found that nitromethane (CH3NO2) can be activated into a useful nitrogenating reagent for the synthesis of amide and nitrile compounds. In this work, the mechanisms of CH3NO2 activation are explored in detail… read more here.

Keywords: insights nitromethane; nitromethane activation; activation; reactive nitrogenating ... See more keywords

Mechanistic Insights into Reactions between Gold-Based Materials and Dioxygen.

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recommendations! Published in 2025 at "ChemPlusChem"

DOI: 10.1002/cplu.202500244

Abstract: Gold (Au) exhibits distinct reactivities with O2 at the nanometer to atomic scales, whereas bulk Au is chemically inert. Since the discovery of catalytic reactivities in Au-based materials, including nanoparticles, molecular complexes, and nanoclusters (AuNCs),… read more here.

Keywords: mechanistic insights; materials dioxygen; gold based; insights reactions ... See more keywords
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Mechanistic Insights into the Unique Role of Copper in CO2 Electroreduction Reactions.

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recommendations! Published in 2017 at "ChemSusChem"

DOI: 10.1002/cssc.201601144

Abstract: Cu demonstrates a unique capability towards CO2 electroreduction that can close the anthropogenic carbon cycle; however, its reaction mechanism remains elusive, owing to the obscurity of the solid-liquid interface on Cu surfaces where electrochemical reactions… read more here.

Keywords: unique role; insights unique; electroreduction; co2 electroreduction ... See more keywords

Active Sites for CO2 Hydrogenation to Methanol: Mechanistic Insights and Reaction Control.

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recommendations! Published in 2024 at "ChemSusChem"

DOI: 10.1002/cssc.202401846

Abstract: Catalytic CO2 conversion to methanol is a promising way to extenuate the adverse effects of CO2 emission, global warming and energy shortage. Understanding the fundamental features of CO2 activation and hydrogenation at the molecular level… read more here.

Keywords: mechanistic insights; hydrogenation; active sites; hydrogenation methanol ... See more keywords

Mechanistic insights on nsSNPs on binding site of renin and cytochrome P450 proteins: A computational perceptual study for pharmacogenomics evaluation

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recommendations! Published in 2021 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.30069

Abstract: Past several decades, therapeutic investigations lead to the discovery of numerous antihypertensive drugs. Although it has been proved for their potency, altered efficacy is common norms in several conditions due to genetic variations. Cytochrome P450… read more here.

Keywords: study; drug; drug molecules; cytochrome p450 ... See more keywords