Mechanistic Investigation of Biocatalytic Heme Carbenoid Si−H Insertions
Sign Up to like & getrecommendations! Published in 2019 at "ChemCatChem"
DOI: 10.1002/cctc.201801755
Abstract: Recent studies reported the development of biocatalytic heme carbenoid Si−H insertions for the selective formation of carbon‐silicon bonds, but many mechanistic questions remain unaddressed. To this end, a DFT mechanistic investigation was performed which reveals… read more here.
Keywords: heme; biocatalytic heme; carbenoid insertions; heme carbenoid ... See more keywords
Iodine/DMSO promoted oxidation of benzylic Csp3–H bonds to diketones – A mechanistic investigation
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.130617
Abstract: Abstract This article describes a mechanistic investigation into the I2/DMSO mediated benzylic Csp3–H oxidation of an α-methylene ketone. The electron paramagnetic resonance (EPR) spectrum centred at g = 2.0011 supports the involvement of iodine and benzylic radicals,… read more here.
Keywords: benzylic csp3; dmso; oxidation; mechanistic investigation ... See more keywords
Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Research in Toxicology"
DOI: 10.1021/acs.chemrestox.2c00210
Abstract: The oral antiparasitic drug nifurtimox has been used to treat Chagas disease for more than 50 years. Historical studies determined that very little nifurtimox is excreted unchanged, but contemporaneous preclinical studies of radiolabeled nifurtimox found… read more here.
Keywords: metabolism nifurtimox; metabolism; structural mechanistic; mechanistic investigation ... See more keywords
Mechanistic Investigation of Inclusion Complexes of a Sulfa Drug with α- and β-Cyclodextrins
Sign Up to like & getrecommendations! Published in 2017 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.7b02619
Abstract: Molecular encapsulation is extremely important in pharmaceutical and drug delivery science. In this article, one of the most important sulfa drugs, namely, sulfacetamide sodium, has been probed in the solution and solid phases for encapsulation… read more here.
Keywords: inclusion; complexes sulfa; drug; investigation inclusion ... See more keywords
Mechanistic Investigation of the Synthesis of Dianionic In-Derived Coordination Polymers.
Sign Up to like & getrecommendations! Published in 2023 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.3c00148
Abstract: The mechanism of formation of crystalline coordination polymers is as complex as the architectures themselves. In this Communication, we detail a three-tiered approach using density functional theory (DFT) analysis, synthesis, and in situ Raman spectroscopy… read more here.
Keywords: coordination; synthesis; derived coordination; coordination polymers ... See more keywords
An in-depth mechanistic investigation of the radical initiation behavior of monoacylgermanes
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecules"
DOI: 10.1021/acs.macromol.7b01721
Abstract: Five para-substituted monoacyltrimethylgermane derivatives, i.e., p-fluorobenzoyltrimethylgermane (pFBG, λmax = 405 nm), p-methoxybenzoyltrimethylgermane (pMBG, λmax = 397 nm), benzoyltrimethylgermane (pHBG, λmax = 409 nm), p-cyanobenzoyltrimethylgermane (pCBG, λmax = 425 nm), and p-nitrobenzoyltrimethylgermane (pNBG, λmax = 429… read more here.
Keywords: investigation radical; initiation; initiation behavior; depth mechanistic ... See more keywords
Mechanistic Investigation of the Nickel-Catalyzed Carbonylation of Alcohols
Sign Up to like & getrecommendations! Published in 2020 at "Organometallics"
DOI: 10.1021/acs.organomet.0c00082
Abstract: The carbonylation of alcohols represents a straightforward and atom-efficient methodology for the preparation of carboxylic acids. It is desirable to perform these reactions under precious metal-fr... read more here.
Keywords: carbonylation alcohols; investigation nickel; carbonylation; catalyzed carbonylation ... See more keywords
Mechanistic Investigation of Water Oxidation Catalyzed by Uniform, Assembled MnO Nanoparticles.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.6b10657
Abstract: The development of active water oxidation catalysts is critical to achieve high efficiency in overall water splitting. Recently, sub-10 nm-sized monodispersed partially oxidized manganese oxide nanoparticles were shown to exhibit not only superior catalytic performance… read more here.
Keywords: water; mechanistic investigation; water oxidation; mno nanoparticles ... See more keywords
Mechanistic Investigation and Multiplexing of Liposome-Assisted Metabolic Glycan Labeling.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b10990
Abstract: Metabolic labeling of glycans with bioorthogonal reporters has been widely used for glycan imaging and glycoproteomic profiling. One of the intrinsic limitations of metabolic glycan labeling is the lack of cell-type selectivity. The recently developed… read more here.
Keywords: metabolic glycan; labor; glycan labeling; liposome assisted ... See more keywords
Mechanistic investigation into the C(sp3)–H acetoxylation of morpholinones† †Electronic supplementary information (ESI) available: Experimental procedures, characterization data and kinetic details. See DOI: 10.1039/c8sc03434f
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c8sc03434f
Abstract: The study of a selective palladium(ii)-catalyzed C(sp3)–H acetoxylation reaction on a class of cyclic alkyl amines is reported. read more here.
Keywords: acetoxylation morpholinones; morpholinones electronic; acetoxylation; investigation sp3 ... See more keywords
Oxidative cleavage of cycloalkenes using hydrogen peroxide and a tungsten-based catalyst: towards a complete mechanistic investigation
Sign Up to like & getrecommendations! Published in 2021 at "New Journal of Chemistry"
DOI: 10.1039/d0nj03592k
Abstract: The identification of the intermediates and by-products produced during the oxidative cleavage of cycloalkenes in the presence of H2O2 and a tungsten-based catalyst for the production of dicarboxylic acids has been carried out under various… read more here.
Keywords: based catalyst; oxidative cleavage; cleavage cycloalkenes; tungsten based ... See more keywords