Mechanistic Investigations on Hydrogenation, Isomerization and Hydrosilylation Reactions Mediated by a Germyl‐Rhodium System
Sign Up to like & getrecommendations! Published in 2022 at "Chemcatchem"
DOI: 10.1002/cctc.202200157
Abstract: We recently disclosed a dehydrogenative double C−H bond activation reaction in the unusual pincer‐type rhodium‐germyl complex [(ArMes)2ClGeRh] (ArMes=C6H3‐2,6‐(C6H2‐2,4,6‐Me3)2). Herein we investigate the catalytic applications of this Rh/Ge system in several transformations, namely trans‐semihydrogenation of internal… read more here.
Keywords: system; semihydrogenation internal; rhodium; mechanistic investigations ... See more keywords
Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition**
Sign Up to like & getrecommendations! Published in 2021 at "Chemmedchem"
DOI: 10.1002/cmdc.202100042
Abstract: Metallo‐β‐lactamases (MBLs) are zinc‐dependent bacterial enzymes that inactivate essentially all classes of β‐lactam antibiotics including last‐resort carbapenems. At present there are no clinically approved MBL inhibitors, and in order to develop such agents it is… read more here.
Keywords: zinc; investigations metallo; mechanistic investigations; inhibition ... See more keywords
Application of Pulse Radiolysis to Mechanistic Investigations of Catalysis Relevant to Artificial Photosynthesis.
Sign Up to like & getrecommendations! Published in 2017 at "ChemSusChem"
DOI: 10.1002/cssc.201701559
Abstract: Taking inspiration from natural photosystems, the goal of artificial photosynthesis is to harness solar energy to convert abundant materials, such as CO2 and H2 O, into solar fuels. Catalysts are required to ensure that the… read more here.
Keywords: mechanistic investigations; relevant artificial; pulse radiolysis; radiolysis ... See more keywords
Mechanistic investigations in ultrasound-assisted biodegradation of phenanthrene.
Sign Up to like & getrecommendations! Published in 2019 at "Ultrasonics sonochemistry"
DOI: 10.1016/j.ultsonch.2019.104890
Abstract: This study has addressed the biodegradation of polycyclic aromatic hydrocarbon, phenanthrene using Candida tropicalis. Optimization using central composite statistical design yielded optimum experimental parameters as: pH = 6.2, temperature = 33.4 °C, mechanical shaking = 190 rpm and % inoculum = 9.26% v/v. Sonication of… read more here.
Keywords: phenanthrene; investigations ultrasound; biodegradation; mechanistic investigations ... See more keywords
Mechanistic Investigations of Reactions of the Frustrated Lewis Pairs (Triarylphosphines/B(C6F5)3) with Michael Acceptors.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.6b03868
Abstract: Frustrated Lewis pair (FLP)-catalyzed reduction of Michael acceptors is a challenging reaction that proceeds with specific FLP structures. Kinetics and equilibrium of the reactions of two phosphines (Ar3P), namely tri(1-naphthyl)phosphine and tri(o-tolyl)phosphine, are reported with… read more here.
Keywords: lewis pairs; investigations reactions; mechanistic investigations; reactions frustrated ... See more keywords
Mechanistic Investigations on N-Cα Bond Cleavages in Dibasic Peptides Containing Internal Lys and Arg Residues.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00055
Abstract: The model nonapeptide AAARAAKAG* (* indicates amide) is used to explore N-Cα bond fragmentation under CID-MS conditions. Neighboring group participation and the effect of positioning of Lys and Arg residues on N-Cα bond cleavage is… read more here.
Keywords: arg residues; arg; mechanistic investigations; lys arg ... See more keywords
Mechanistic investigations and molecular properties of 1,2-bis(ferrocenyl)dimetallenes including group 14 elements
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra04935h
Abstract: The molecular properties and reactive activities of the d-π conjugated (E)-Tip(Fc)E14E14(Fc)Tip (1-C, 1-Si, 1-Ge, 1-Sn, and 1-Pb) systems possessing the E14E14 unit were explored using density functional theory (M06-2X/Def2-SVPD). The theoretical investigations on the basis… read more here.
Keywords: investigations molecular; molecular properties; mechanistic investigations; group ... See more keywords
Tandem double hydrophosphination of α,β,γ,δ-unsaturated-1,3-indandiones: diphosphine synthesis, mechanistic investigations and coordination chemistry.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc05384k
Abstract: A metal-free tandem double hydrophosphination of extended conjugated indandiones has been established. Mechanistic investigations confirmed the consecutive manner of the nucleophilic addition reaction. Complexation of the generated keto-diphosphine resulted in the formation of an unexpected… read more here.
Keywords: coordination; tandem double; mechanistic investigations; chemistry ... See more keywords
Mechanistic Investigations Support Liver Safety of Ubrogepant
Sign Up to like & getrecommendations! Published in 2020 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfaa093
Abstract: Abstract Small-molecule calcitonin gene-related peptide (CGRP) receptor antagonists have demonstrated therapeutic efficacy for the treatment of migraine. However, previously investigated CGRP receptor antagonists, telcagepant and MK-3207, were discontinued during clinical development because of concerns about… read more here.
Keywords: cgrp receptor; telcagepant 3207; support liver; mechanistic investigations ... See more keywords
Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs
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DOI: 10.1093/toxsci/kfx035
Abstract: &NA; Nitrated polycyclic aromatic hydrocarbons (NPAHs) and heterocyclic PAHs (HPAHs) are recognized environmental pollutants. However, the health risks of NPAHs and HPAHs to humans and environmental systems are not well‐studied. The developmental zebrafish (Danio rerio)… read more here.
Keywords: mechanistic investigations; heterocyclic pahs; investigations developmental; toxicity ... See more keywords
Mechanistic Investigations of Nickamine- catalyzed Hydrosilylation of Alkenes: Nickel Nanoparticles Are the Active Species.
Sign Up to like & getrecommendations! Published in 2020 at "Chimia"
DOI: 10.2533/chimia.2020.444
Abstract: Hydrosilylation is an important chemical process for the synthesis of organosilanes and for the production of silicone polymers. The wide variety of catalysts developed for this reaction generally follow a Chalk-Harrod, or a sigma-bond metathesis… read more here.
Keywords: hydrosilylation alkenes; mechanistic investigations; investigations nickamine; nickamine catalyzed ... See more keywords