The case for the therapeutic use of mechanistic/mammalian target of rapamycin (mTOR) inhibitors in xenotransplantation.
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DOI: 10.1111/xen.12802
Abstract: The mechanistic/mammalian target of rapamycin (mTOR) is one of the systems that are necessary to maintain cell homeostasis, such as survival, proliferation, and differentiation. mTOR inhibitors (mTOR‐Is) are utilized as immunosuppressants and anti‐cancer drugs. In… read more here.
Keywords: target rapamycin; mtor inhibitors; mechanistic mammalian; mammalian target ... See more keywords