Articles with "mechanistic model" as a keyword



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Importance of Initial Concentration of Factor VIII in a Mechanistic Model of In Vitro Coagulation

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Published in 2018 at "Acta Biotheoretica"

DOI: 10.1007/s10441-018-9329-8

Abstract: This computational study generates a hypothesis for the coagulation protein whose initial concentration greatly influences the course of coagulation. Many clinical malignancies of blood coagulation arise due to abnormal initial concentrations of coagulation factors. Sensitivity… read more here.

Keywords: coagulation; mechanistic model; model; initial concentration ... See more keywords
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Development of a mechanistic model for sliding bubbles growth prediction in subcooled boiling flow

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Published in 2018 at "Applied Thermal Engineering"

DOI: 10.1016/j.applthermaleng.2018.04.096

Abstract: Abstract A new mechanistic model for predicting the growth of sliding bubbles in subcooled boiling flow has been developed. The basis of this model is the assumption that the fundamental heat transfer mechanisms acting on… read more here.

Keywords: bubble growth; mechanistic model; model; subcooled boiling ... See more keywords
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A mechanistic model of erythroblast growth inhibition providing a framework for optimisation of cell therapy manufacturing

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Published in 2018 at "Biochemical Engineering Journal"

DOI: 10.1016/j.bej.2018.01.033

Abstract: Abstract Manufacture of Red Blood Cell based products in vitro requires highly efficient erythroblast culture for economic viability. It has previously been shown that efficiency of erythroblast culture in scalable bioreactors is not primarily limited… read more here.

Keywords: cell; medium; mechanistic model; inhibition ... See more keywords
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A comprehensive mechanistic model for simulating algal-bacterial growth dynamics in photobioreactors.

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Published in 2018 at "Bioresource technology"

DOI: 10.1016/j.biortech.2017.09.093

Abstract: A comprehensive mechanistic model with state of the art understanding and assumptions is presented to simulate major processes in a photobioreactor for describing the algal-bacterial growth dynamics. The model includes a total of 37 state… read more here.

Keywords: comprehensive mechanistic; growth dynamics; mechanistic model; algal bacterial ... See more keywords
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Mechanistic model for Francis turbines in OpenModelica

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Published in 2018 at "IFAC-PapersOnLine"

DOI: 10.1016/j.ifacol.2018.03.018

Abstract: Abstract Often, simulation tools use an empirical turbine model, typically based on look-up tables for turbine efficiency. Such look-up tables can be based on dimensionless hill charts which again require experimental data, or can be… read more here.

Keywords: turbine; mechanistic model; model; design algorithm ... See more keywords
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Predicting the ductile failure of Al5083-H116 specimens with a mechanistic model and no free fitting parameters

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Published in 2017 at "International Journal of Solids and Structures"

DOI: 10.1016/j.ijsolstr.2017.02.025

Abstract: Abstract A mechanistic model that does not depend on free fitting parameters was developed for predicting the ductile failure of Al 5083-H116. The model takes three inputs: (1) the large deformation constitutive response of the… read more here.

Keywords: ductile failure; mechanistic model; free fitting; model ... See more keywords
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Toward the General Mechanistic Model of Liquid Chromatographic Retention.

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Published in 2022 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.2c02034

Abstract: Large datasets of chromatographic retention times are relatively easy to collect. This statement is particularly true when mixtures of compounds are analyzed under a series of gradient conditions using chromatographic techniques coupled with mass spectrometry… read more here.

Keywords: retention; chromatographic retention; analyte specific; toward general ... See more keywords
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Mechanistic Model To Predict Hydrate Deposition under Stratified Flow Conditions

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Published in 2019 at "Energy & Fuels"

DOI: 10.1021/acs.energyfuels.9b01624

Abstract: Gas hydrate formation in pipelines is considered as a serious flow assurance threat to oil and gas production. The severity can be realized from its rapid tendency to form plugs and impede production. The assessment… read more here.

Keywords: mechanistic model; stratified flow; deposition; model ... See more keywords
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Mechanistic Model for the Hsp90-Driven Opening of Human Argonaute

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Published in 2020 at "Journal of Chemical Information and Modeling"

DOI: 10.1021/acs.jcim.0c00053

Abstract: The assembly of RNA-induced silencing complex (RISC) is a key process in small RNA-mediated gene silencing. Loading of small RNAs into Argonaute (Ago), the key player protein in the process, has been shown to depend… read more here.

Keywords: hsp90 driven; hsp90; hago2; mechanistic model ... See more keywords
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Simplified Mechanistic Model for Seismic Response Prediction of Coupled Cross-Laminated Timber Rocking Walls

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Published in 2019 at "Journal of Structural Engineering"

DOI: 10.1061/(asce)st.1943-541x.0002265

Abstract: AbstractA simplified mechanistic model is developed in this study to predict the lateral load resistance of coupled rocking walls made from cross-laminated timber (CLT) panels as an alternative to ... read more here.

Keywords: mechanistic model; simplified mechanistic; rocking walls; laminated timber ... See more keywords
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A mechanistic model of energy consumption in milling

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Published in 2018 at "International Journal of Production Research"

DOI: 10.1080/00207543.2017.1404160

Abstract: In this paper, a novel mechanistic model is proposed and validated for the consumption of energy in milling processes. The milling machine is considered as a thermodynamic system. Mechanisms of the significant energy conversion processes… read more here.

Keywords: machine; energy consumption; energy; mechanistic model ... See more keywords