Anticryptococcal activity and mechanistic studies of short amphipathic peptides
Sign Up to like & getrecommendations! Published in 2023 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200576
Abstract: Cryptococcus neoformans, an opportunistic fungal pathogen, causes cryptococcosis in immunocompromised persons. A series of modified L‐histidines‐containing peptides are synthesized that exhibit promising activity against C. neoformans. Analog 11d [L‐His(2‐adamantyl)‐L‐Trp‐L‐His(2‐phenyl)‐OMe] produced potency with an IC50 of… read more here.
Keywords: short amphipathic; studies short; activity mechanistic; anticryptococcal activity ... See more keywords
A review on comparative mechanistic studies of antimicrobial peptides against archaea
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26387
Abstract: Archaea was until recently considered as a third domain of life in addition to bacteria and eukarya but recent studies support the existence of only two superphyla (bacteria and archaea). The fundamental differences between archaeal,… read more here.
Keywords: review comparative; comparative mechanistic; bacteria eukarya; mechanistic studies ... See more keywords
Mechanistic Studies on the Epoxidation of Alkenes by Macrocyclic Manganese Porphyrin Catalysts
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202200280
Abstract: Abstract Macrocyclic metal porphyrin complexes can act as shape‐selective catalysts mimicking the action of enzymes. To achieve enzyme‐like reactivity, a mechanistic understanding of the reaction at the molecular level is needed. We report a mechanistic… read more here.
Keywords: epoxidation alkenes; cage; mechanistic studies; oxo ligand ... See more keywords
Computational mechanistic studies on persulfate assisted p‐phenylenediamine polymerization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.26943
Abstract: p‐Phenylenediamine (p‐PDA) is a monomer of many important polymers such as kevlar, twaron, poly‐p‐PDA. Most of the noticed polymers formation is initiated by a free‐radical, but their polymerization mechanism is not elucidated computationally. The proposed… read more here.
Keywords: computational mechanistic; mechanistic studies; free radical; kcal mol ... See more keywords
Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11.
Sign Up to like & getrecommendations! Published in 2020 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2020.08.008
Abstract: We previously reported a peptoid ligand for the proteasomal ubiquitin receptor Rpn13 called KDT-11 and demonstrated that this compound is toxic to multiple myeloma cells, but not non-malignant cells. Here, we show that KDT-11 decreases… read more here.
Keywords: studies multiple; kdt; multiple myeloma; mechanistic studies ... See more keywords
Kinetic and mechanistic studies of Fischer-Tropsch synthesis over the nano-structured iron–cobalt–manganese catalyst prepared by hydrothermal procedure
Sign Up to like & getrecommendations! Published in 2017 at "Fuel"
DOI: 10.1016/j.fuel.2017.03.087
Abstract: Abstract The present research work is focused on the kinetic and mechanistic studies of the Fischer-Tropsch synthesis in a fixed bed micro reactor; over the nano-structured iron–cobalt–manganese catalyst prepared by hydrothermal procedure. Experimental conditions within… read more here.
Keywords: studies fischer; kinetic mechanistic; nano structured; mechanistic studies ... See more keywords
Mechanistic Studies for Pd(II)(O2) Reduction Generating Pd(0) and H2O: Formation of Pd(OH)2 as a Key Intermediate.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c01139
Abstract: Molecular oxygen (O2) remains to be an ideal yet underutilized feedstock for the oxidative transformation of organic substrates and renewable energy systems such as fuel cells. Palladium (Pd) has shown particular promise in enabling these… read more here.
Keywords: studies reduction; reaction; mechanistic studies; reduction generating ... See more keywords
Mechanistic Studies of Alkyne Hydroboration by a Well-Defined Iron Pincer Complex: Direct Comparison of Metal-Hydride and Metal-Boryl Reactivity.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c01325
Abstract: Iron-hydride and iron-boryl complexes supported by a pyrrole-based pincer ligand, tBuPNP (PNP = anion of 2,5-bis(di-tert-butylphosphinomethyl)pyrrole), were employed for a detailed mechanistic study on the hydroboration of internal alkynes. Several novel complexes were isolated and… read more here.
Keywords: boryl; mechanistic studies; iron; hydroboration ... See more keywords
Mechanistic Studies of Carbonyl Allylation Mediated by (NHC)CuH: Isoprene Insertion, Allylation, and β-Hydride Elimination.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c03402
Abstract: The ability of Cu-H complexes to undergo selective insertion of unsaturated hydrocarbons under mild conditions has rendered them valuable, versatile catalysts. The direct formation of Cu allyl intermediates from unfunctionalized 1,3-dienes and transient Cu hydrides… read more here.
Keywords: carbonyl allylation; mechanistic studies; nhc cuh; allylation ... See more keywords
Mechanistic Studies on the Synthesis of Pyrrolidines and Piperidines via Copper-Catalyzed Intramolecular C–H Amination
Sign Up to like & getrecommendations! Published in 2022 at "Organometallics"
DOI: 10.1021/acs.organomet.2c00095
Abstract: We have recently developed a method for the synthesis of pyrrolidines and piperidines via intramolecular C–H amination of N-fluoride amides using [TpxCuL] complexes as precatalysts [Tpx = tris(pyrazolyl)borate ligand and L = THF or CH3CN].… read more here.
Keywords: copper; pyrrolidines piperidines; mechanistic studies; piperidines via ... See more keywords
Nondirected, Cu-Catalyzed sp3 C-H Aminations with Hydroxylamine-Based Amination Reagents: Catalytic and Mechanistic Studies.
Sign Up to like & getrecommendations! Published in 2017 at "Organometallics"
DOI: 10.1021/acs.organomet.7b00003
Abstract: This work demonstrates the use of hydroxylamine-based amination reagents RSO2NH-OAc for the nondirected, Cu-catalyzed amination of benzylic C-H bonds. The amination reagents can be prepared on a gram scale, are benchtop stable, and provide benzylic… read more here.
Keywords: amination reagents; hydroxylamine based; based amination; mechanistic studies ... See more keywords