Association of genetic polymorphisms in the pore domains of mechano‐gated TREK‐1 channel with overactive lower urinary tract symptoms in humans
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DOI: 10.1002/nau.23862
Abstract: Mechanosensitivity of the urinary bladder is regulated by many factors including mechano‐gated two‐pore domain (K2P, KCNK) potassium channels. TWIK‐related K+ channel, TREK‐1, is a predominantly expressed member of K2P channel family in the human detrusor,… read more here.
Keywords: urinary tract; overactive lower; mechano gated; tract symptoms ... See more keywords
Stretch-activated current in human atrial myocytes and Na+ current and mechano-gated channels’ current in myofibroblasts alter myocyte mechanical behavior: a computational study
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DOI: 10.1186/s12938-019-0723-5
Abstract: BackgroundThe activation of stretch-activated channels (SACs) in cardiac myocytes, which changes the phases of action potential repolarization, is proven to be highly efficient for the conversion of atrial fibrillation. The expression of Na+ current in… read more here.
Keywords: stretch activated; gated channels; mechano gated; activated current ... See more keywords