Engineered Extracellular Matrices with Integrated Wireless Microactuators to Study Mechanobiology.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202102641
Abstract: Mechanobiology explores how forces regulate cell behaviors and what molecular machinery are responsible for the sensing, transduction, and modulation of mechanical cues. To this end, probing of cells cultured on planar substrates has served as… read more here.
Keywords: extracellular matrices; matrices integrated; engineered extracellular; mechanobiology ... See more keywords
A novel system for dynamic stretching of cell cultures reveals the mechanobiology for delivering better negative pressure wound therapy
Sign Up to like & getrecommendations! Published in 2020 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-020-01377-6
Abstract: Serious wounds, both chronic and acute (e.g., surgical), are among the most common, expensive and difficult-to-treat health problems. Negative pressure wound therapy (NPWT) is considered a mainstream procedure for treating both wound types. Soft tissue… read more here.
Keywords: pressure wound; mechanobiology; wound; negative pressure ... See more keywords
Science by the sea: how nanoengineering met mechanobiology in Camogli
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical Reviews"
DOI: 10.1007/s12551-019-00598-z
Abstract: Lingering under the last rays of sun, I looked up above. Large windows on a wall were framing what appeared to be a small conference room. I could see a man at the far side… read more here.
Keywords: nanoengineering met; sea nanoengineering; mechanobiology; sea ... See more keywords
The benefits of writing a Review
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical Reviews"
DOI: 10.1007/s12551-019-00600-8
Abstract: The articles are written by a collection of physicists and engineers working at the biophysics/medical engineering interface. They cover the full armamentarium ofmicron to nanometer scale engineering, manipulation and observation methodologies (including the most modern… read more here.
Keywords: writing review; mechanobiology; issue; benefits writing ... See more keywords
Steering cell behavior through mechanobiology in 3D: A regenerative medicine perspective.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120572
Abstract: Mechanobiology, translating mechanical signals into biological ones, greatly affects cellular behavior. Steering cellular behavior for cell-based regenerative medicine approaches requires a thorough understanding of the orchestrating molecular mechanisms, among which mechanotransducive ones are being more… read more here.
Keywords: medicine; mechanobiology; mscs; cell ... See more keywords
Mechanogenetics: harnessing mechanobiology for cellular engineering.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2021.09.011
Abstract: 'Mechanogenetics,' a new field at the convergence of mechanobiology and synthetic biology, presents an innovative strategy to treat, repair, or restore diseased cells and tissues by harnessing mechanical signal transduction pathways to control gene expression.… read more here.
Keywords: cellular engineering; harnessing mechanobiology; mechanobiology; biology ... See more keywords
Soft pneumatic actuators for mimicking multi-axial femoropopliteal artery mechanobiology
Sign Up to like & getrecommendations! Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac63ef
Abstract: Tissue biomanufacturing aims to produce lab-grown stem cell grafts and biomimetic drug testing platforms but remains limited in its ability to recapitulate native tissue mechanics. The emerging field of soft robotics aims to emulate dynamic… read more here.
Keywords: artery; mechanobiology; multi axial; femoropopliteal artery ... See more keywords
ANISE: an application to design mechanobiology simulations of planar epithelia
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac511
Abstract: SUMMARY TiFoSi is an efficient computational tool for performing mechanobiology simulations of planar epithelia. A drawback of this tool is that it relies on an XML configuration file (input data) that can be cumbersome to… read more here.
Keywords: application; anise; planar epithelia; mechanobiology ... See more keywords
A Review of in vitro Platforms for Understanding Cardiomyocyte Mechanobiology
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2019.00133
Abstract: Mechanobiology—a cell's interaction with its physical environment—can influence a myriad of cellular processes including how cells migrate, differentiate and proliferate. In many diseases, remodeling of the extracellular matrix (ECM) is observed such as tissue stiffening… read more here.
Keywords: mechanobiology; cardiomyocyte mechanobiology; vitro platforms; review vitro ... See more keywords
Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2021.826867
Abstract: Discogenic back pain is one of the most diffused musculoskeletal pathologies and a hurdle to a good quality of life for millions of people. Existing therapeutic options are exclusively directed at reducing symptoms, not at… read more here.
Keywords: review; mechanobiology; model; intervertebral disc ... See more keywords
Dynamic Load Model Systems of Tendon Inflammation and Mechanobiology
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.896336
Abstract: Dynamic loading is a shared feature of tendon tissue homeostasis and pathology. Tendon cells have the inherent ability to sense mechanical loads that initiate molecular-level mechanotransduction pathways. While mature tendons require physiological mechanical loading in… read more here.
Keywords: model systems; inflammation; mechanobiology; pathology ... See more keywords