Mechanosensitive Channel-Based Optical Membrane Tension Reporter.
Sign Up to like & getrecommendations! Published in 2023 at "ACS sensors"
DOI: 10.1021/acssensors.2c01921
Abstract: Plasma membrane tension functions as a global physical organizer of cellular activities. Technical limitations of current membrane tension measurement techniques have hampered in-depth investigation of cellular membrane biophysics and the role of plasma membrane tension… read more here.
Keywords: optical membrane; tension reporter; membrane tension; mechanosensitive channel ... See more keywords
Upregulation of mechanosensitive channel Piezo1 involved in high shear stress-induced pulmonary hypertension.
Sign Up to like & getrecommendations! Published in 2022 at "Thrombosis research"
DOI: 10.22541/au.164382289.90069251/v1
Abstract: INTRODUCTION Piezo1 is an important mechanosensitive channel implicated in vascular remodeling. However, the role of Piezo1 in different types of vascular cells during the development of pulmonary hypertension (PH) induced by high shear stress is… read more here.
Keywords: stress; lpal rats; upregulation; mechanosensitive channel ... See more keywords
In Silico Screen Identifies a New Family of Agonists for the Bacterial Mechanosensitive Channel MscL
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11040433
Abstract: MscL is a highly conserved mechanosensitive channel found in the majority of bacterial species, including pathogens. It functions as a biological emergency release valve, jettisoning solutes from the cytoplasm upon acute hypoosmotic stress. It opens… read more here.
Keywords: mscl; mechanosensitive channel; silico screen; channel ... See more keywords
Activation of a Bacterial Mechanosensitive Channel, MscL, Underlies the Membrane Permeabilization of Dual-Targeting Antibacterial Compounds
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DOI: 10.3390/antibiotics11070970
Abstract: Resistance to antibiotics is a serious and worsening threat to human health worldwide, and there is an urgent need to develop new antibiotics that can avert it. One possible solution is the development of compounds… read more here.
Keywords: bacterial mechanosensitive; membrane permeabilization; mscl; resistance ... See more keywords
The Role of the Piezo1 Mechanosensitive Channel in the Musculoskeletal System
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076513
Abstract: Since the recent discovery of the mechanosensitive Piezo1 channels, many studies have addressed the role of the channel in various physiological or even pathological processes of different organs. Although the number of studies on their… read more here.
Keywords: system; piezo1 mechanosensitive; mechanosensitive channel; role piezo1 ... See more keywords