Corynebacterium glutamicum mechanosensitive channels: towards unpuzzling “glutamate efflux” for amino acid production
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical Reviews"
DOI: 10.1007/s12551-018-0452-1
Abstract: Corynebacterium glutamicum has been utilized for industrial amino acid production, especially for monosodium glutamate (MSG), the food-additive for the “UMAMI” category of taste sensation, which is one of the five human basic tastes. Glutamate export… read more here.
Keywords: acid production; amino acid; corynebacterium glutamicum; glutamate ... See more keywords
Mechanosensitive channels of Corynebacterium glutamicum functioning as exporters of l-glutamate and other valuable metabolites.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2020.05.005
Abstract: In the industrial l-glutamate production established on the use of Corynebacterium glutamicum, l-glutamate synthesized intracellularly is exported through mechanosensitive transmembrane channel proteins (MscCG and MscCG2) activated by the force-from-lipids. The involvement of MscCG2 in l-glutamate… read more here.
Keywords: channels corynebacterium; glutamicum; corynebacterium glutamicum; glutamate ... See more keywords
"Force-from-lipids" gating of mechanosensitive channels modulated by PUFAs.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2017.12.026
Abstract: The level of fatty acid saturation in phospholipids is a crucial determinant of the biophysical properties of the lipid bilayer. Integral membrane proteins are sensitive to changes of their bilayer environment such that their activities… read more here.
Keywords: lipids gating; poly unsaturated; ion; membrane ... See more keywords
Cryo-EM Structure of Mechanosensitive Channel YnaI Using SMA2000: Challenges and Opportunities
Sign Up to like & getrecommendations! Published in 2021 at "Membranes"
DOI: 10.3390/membranes11110849
Abstract: Mechanosensitive channels respond to mechanical forces exerted on the cell membrane and play vital roles in regulating the chemical equilibrium within cells and their environment. High-resolution structural information is required to understand the gating mechanisms… read more here.
Keywords: ynai; transmembrane domain; sma2000; structure ... See more keywords