Mechanosensitivity of microdomain calcium signalling in the heart.
Sign Up to like & getrecommendations! Published in 2017 at "Progress in biophysics and molecular biology"
DOI: 10.1016/j.pbiomolbio.2017.06.013
Abstract: In cardiac myocytes, calcium (Ca2+) signalling is tightly controlled in dedicated microdomains. At the dyad, i.e. the narrow cleft between t-tubules and junctional sarcoplasmic reticulum (SR), many signalling pathways combine to control Ca2+-induced Ca2+ release… read more here.
Keywords: mechanosensitivity; microdomain calcium; local ca2; mechanosensitivity microdomain ... See more keywords
Structure-guided examination of the mechanogating mechanism of PIEZO2
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1905985116
Abstract: Significance Aristotle’s five senses—sight, smell, taste, hearing, and touch—are crucial for the perception of and interaction with the environment. While the molecular machineries that detect visual, olfactory, gustatory, and auditory stimuli are well characterized, comparatively… read more here.
Keywords: mechanosensitivity; mechanogating mechanism; mechanism piezo2; piezo2 ... See more keywords
Neuromuscular Mechanosensitivity in Subjects with Chronic Ankle Sprain: A Cross-Sectional Study.
Sign Up to like & getrecommendations! Published in 2019 at "Pain medicine"
DOI: 10.1093/pm/pny299
Abstract: Background Ankle sprain is one of the most common musculoskeletal injuries in sports, at work, and at home. Subjects who suffer from this injury may develop ankle instability. Functional instability has been associated with a… read more here.
Keywords: mechanosensitivity; cross sectional; ankle; ankle sprain ... See more keywords
The "Stressful" Life of Cell Adhesion Molecules: On the Mechanosensitivity of Integrin Adhesome.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4038812
Abstract: Cells have evolved into complex sensory machines that communicate with their microenvironment via mechanochemical signaling. Extracellular mechanical cues trigger complex biochemical pathways in the cell, which regulate various cellular processes. Integrin-mediated focal adhesions (FAs) are… read more here.
Keywords: mechanosensitivity; life cell; cell adhesion; integrin adhesome ... See more keywords
Immediate Effects of Acupuncture on the Mechanosensitivity of the Median Nerve: An Exploratory Randomised Trial
Sign Up to like & getrecommendations! Published in 2018 at "Acupuncture in Medicine"
DOI: 10.1136/acupmed-2016-011357
Abstract: Background Acupuncture appears to reduce the mechanosensitivity of peripheral nerves in animal models; yet, this possibility has not been demonstrated in humans. Objectives The main objective of this exploratory trial was to evaluate the immediate… read more here.
Keywords: mechanosensitivity; acupuncture mechanosensitivity; effects acupuncture; trial ... See more keywords
Mechanosensitivity is an essential component of phototransduction in vertebrate rods
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3000750
Abstract: Photoreceptors are specialized cells devoted to the transduction of the incoming visual signals. Rods are able also to shed from their tip old disks and to synthesize at the base of the outer segment (OS)… read more here.
Keywords: mechanosensitivity; essential component; component phototransduction; phototransduction ... See more keywords
Pre-strains and buckling in mechanosensitivity of contractile cells and focal adhesions: A tensegrity model.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.2139/ssrn.4142057
Abstract: We demonstrate that several key aspects of the contractile activity of a cell interacting with the substrate can be captured by means of a non linear elastic tensegrity mechanical system made of a tensile element… read more here.
Keywords: tensegrity; buckling mechanosensitivity; strains buckling; pre strains ... See more keywords
No immediate changes on neural and muscular mechanosensitivity after first rib manipulation in subjects with cervical whiplash: A randomized controlled trial.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of back and musculoskeletal rehabilitation"
DOI: 10.3233/bmr-160645
Abstract: BACKGROUND Upper rib manipulative therapy appears to be effective on primary complaint of shoulder pain, but its efficacy has not been evaluated in subjects with whiplash-associated disorders. OBJECTIVE To assess the immediate changes on neural… read more here.
Keywords: first rib; muscular mechanosensitivity; mechanosensitivity; neural muscular ... See more keywords
Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.662410
Abstract: The understanding of the electrophysiological mechanisms that underlie mechanosensitivity of the sinoatrial node (SAN), the primary pacemaker of the heart, has been evolving over the past century. The heart is constantly exposed to a dynamic… read more here.
Keywords: sinoatrial node; mechanosensitivity; electrophysiological molecular; node mechanosensitivity ... See more keywords
Mechanosensitivity of Murine Lung Slowly Adapting Receptors: Minimal Impact of Chemosensory, Serotonergic, and Purinergic Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.833665
Abstract: Murine slowly adapting receptors (SARs) within airway smooth muscle provide volume-related feedback; however, their mechanosensitivity and morphology are incompletely characterized. We explored two aspects of SAR physiology: their inherent static mechanosensitivity and a potential link… read more here.
Keywords: murine; ptr; sar mechanosensitivity; slowly adapting ... See more keywords
Analyzing the Interaction between Clinical, Neurophysiological and Psychological Outcomes Underlying Chronic Plantar Heel Pain: A Network Analysis Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph191610301
Abstract: Plantar heel pain (PHP) is one of the most common foot pain conditions in adults. Several biological and psychological factors could be involved in chronic PHP in a complex matrix. However, reciprocal interactions between these… read more here.
Keywords: network; related variables; pain related; pain ... See more keywords