Differential Regulation of MeCP2 Phosphorylation by Laminin in Oligodendrocytes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-017-0939-4
Abstract: Oligodendrocytes (OLGs) are the myelinating cells of the central nervous system (CNS), and its proper differentiation is crucial for normal functioning of neurons. Methyl-CpG-binding protein 2 (MeCP2) is a multifunctional methylated DNA binding protein; mutation… read more here.
Keywords: mecp2; differential regulation; laminin; mecp2 phosphorylation ... See more keywords
Sustained effects of rapidly acting antidepressants require BDNF-dependent MeCP2 phosphorylation.
Sign Up to like & getrecommendations! Published in 2021 at "Nature neuroscience"
DOI: 10.1038/s41593-021-00868-8
Abstract: The rapidly acting antidepressants ketamine and scopolamine exert behavioral effects that can last from several days to more than a week in some patients. The molecular mechanisms underlying the maintenance of these antidepressant effects are… read more here.
Keywords: ketamine scopolamine; rapidly acting; acting antidepressants; mecp2 phosphorylation ... See more keywords