MEDI1873, a potent, stabilized hexameric agonist of human GITR with regulatory T-cell targeting potential
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DOI: 10.1080/2162402x.2017.1280645
Abstract: ABSTRACT Glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR) is part of a system of signals involved in controlling T-cell activation. Targeting and agonizing GITR in mice promotes antitumor immunity by enhancing the function of effector… read more here.
Keywords: agonist; gitr; medi1873; potent ... See more keywords