Endothelial Contribution to Warfarin-Induced Arterial Media Calcification in Mice
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222111615
Abstract: Arterial media calcification (AMC) is predominantly regulated by vascular smooth muscle cells (VSMCs), which transdifferentiate into pro-calcifying cells. In contrast, there is little evidence for endothelial cells playing a role in the disease. The current… read more here.
Keywords: endothelial contribution; media calcification; calcification; arterial media ... See more keywords
New Therapeutics Targeting Arterial Media Calcification: Friend or Foe for Bone Mineralization?
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12040327
Abstract: The presence of arterial media calcification, a highly complex and multifactorial disease, puts patients at high risk for developing serious cardiovascular consequences and mortality. Despite the numerous insights into the mechanisms underlying this pathological mineralization… read more here.
Keywords: media calcification; arterial media; calcification; bone mineralization ... See more keywords
Molecular and Cellular Mechanisms that Induce Arterial Calcification by Indoxyl Sulfate and P-Cresyl Sulfate
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DOI: 10.3390/toxins12010058
Abstract: The protein-bound uremic toxins, indoxyl sulfate (IS) and p-cresyl sulfate (PCS), are considered to be harmful vascular toxins. Arterial media calcification, or the deposition of calcium phosphate crystals in the arteries, contributes significantly to cardiovascular… read more here.
Keywords: sulfate; sulfate cresyl; media calcification; calcification ... See more keywords