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   Articles with "media milling" as a keyword



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A microhydrodynamic rationale for selection of bead size in preparation of drug nanosuspensions via wet stirred media milling.

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recommendations! Published in 2017 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2017.04.001

Abstract: Although wet stirred media milling has proven to be a robust process for producing nanoparticle suspensions of poorly water-soluble drugs and thereby enhancing their bioavailability, selection of bead size has been largely empirical, lacking fundamental… read more here.

Keywords: bead size; wet stirred; drug; size ... See more keywords
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Online rheological monitoring of stirred media milling

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recommendations! Published in 2017 at "Powder Technology"

DOI: 10.1016/j.powtec.2016.12.021

Abstract: Abstract Authors had developed a tube rheometer to supplement a Netzsch MiniCer (Netzsch GmbH, Germany) stirred media mill in order to monitor online the rheological characteristics of the suspension and therefore the result of grinding… read more here.

Keywords: stirred media; monitoring stirred; rheological monitoring; suspension ... See more keywords
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In vitro performances and cellular uptake of clarithromycin nanocrystals produced by media milling technique

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recommendations! Published in 2018 at "Powder Technology"

DOI: 10.1016/j.powtec.2018.07.036

Abstract: Abstract Nanocrystal technology is one of a promising approach used to improve the solubility of poorly soluble drugs. In this study, media milling technique was used to produce clarithromycin nanocrystals via a bead milling machine.… read more here.

Keywords: clarithromycin; solubility; media milling; clarithromycin nanocrystals ... See more keywords
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Mechanistic Modeling of Wet Stirred Media Milling for Production of Drug Nanosuspensions.

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recommendations! Published in 2020 at "AAPS PharmSciTech"

DOI: 10.1208/s12249-020-01876-w

Abstract: Drug nanocrystals have been used for a wide range of drug delivery platforms in the pharmaceutical industry, especially for bioavailability enhancement of poorly water-soluble drugs. Wet stirred media milling (WSMM) is the most widely used… read more here.

Keywords: stirred media; wet stirred; drug nanosuspensions; mechanistic modeling ... See more keywords