Progression of Medial Arterial Calcification in CKD
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DOI: 10.1016/j.ekir.2018.07.011
Abstract: Introduction Medial arterial calcification is common in chronic kidney disease (CKD) and portends poor clinical outcomes, but its progression relative to the severity of CKD and the role of other risk factors is unknown because… read more here.
Keywords: medial arterial; calcification; progression medial; ckd ... See more keywords
Medial arterial calcification in ageing and disease: current evidence and knowledge gaps.
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DOI: 10.1093/eurheartj/ehaf341
Abstract: Medial arterial calcification (MAC) characterizes human arterial ageing, potentially remaining clinically silent for decades. However, in susceptible individuals and patients with diabetes mellitus and chronic kidney disease, it becomes a critical risk factor for cardiovascular… read more here.
Keywords: ageing disease; mac; disease; medial arterial ... See more keywords
Pedal medial arterial calcification in diabetic foot ulcers: A significant risk factor of amputation and mortality
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DOI: 10.1111/1753-0407.13527
Abstract: Pedal medial arterial calcification (MAC) is frequently observed in individuals with diabetic foot ulcers (DFUs). However, the impact of pedal MAC on individuals with DFUs remains uncertain. The main aim of this study was to… read more here.
Keywords: diabetic foot; medial arterial; arterial calcification; amputation mortality ... See more keywords
Predicting Major Lower Limb Amputations in Chronic Limb-Threatening Ischemia: The Role of Pedal Medial Arterial Calcification
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DOI: 10.1177/15385744251360828
Abstract: Objective: The Pedal Medial Arterial Calcification (pMAC) score is a radiographic tool that quantifies arterial calcification in the foot, providing a novel approach to predict outcomes in chronic limb-threatening ischemia (CLTI). This study investigates the… read more here.
Keywords: limb; medial arterial; arterial calcification; pmac ... See more keywords
Associations of phosphorus concentrations with medial arterial calcification in lower-extremity arteries and diabetic foot in people with diabetes: a retrospective cross-sectional study
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DOI: 10.1186/s12933-024-02361-5
Abstract: The aim of this study was to investigate the associations of blood phosphorus levels with the risk of developing medial arterial calcification (MAC) in lower-limb arteries and diabetic foot (DF) in diabetes patients. We sought… read more here.
Keywords: medial arterial; arterial calcification; phosphorus concentrations; phosphorus ... See more keywords
Establishment of a medial arterial calcification model in C57BL/6J mice via arterial intimal injury
Sign Up to like & getrecommendations! Published in 2025 at "Cardiovascular Diagnosis and Therapy"
DOI: 10.21037/cdt-2025-435
Abstract: Background Medial arterial calcification (MAC) increases vascular stiffness and reduces arterial compliance, often leading to serious systemic vascular diseases. However, research progress in this field has been limited by the lack of effective animal models.… read more here.
Keywords: mice; medial arterial; injury; model ... See more keywords
Inflammatory, Metabolic, and Coagulation Effects on Medial Arterial Calcification in Patients with Peripheral Arterial Disease
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043132
Abstract: Calcium deposits in the vessel wall in the form of hydroxyapatite can accumulate in the intimal layer, as in atherosclerotic plaque, but also in the medial layer, as in medial arterial calcification (MAC) or medial… read more here.
Keywords: calcification; disease; development; medial arterial ... See more keywords