Inactivation of the Medial Entorhinal Cortex Selectively Disrupts Learning of Interval Timing.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108163
Abstract: The entorhinal-hippocampal circuit can encode features of elapsed time, but nearly all previous research focused on neural encoding of "implicit time." Recent research has revealed encoding of "explicit time" in the medial entorhinal cortex (MEC)… read more here.
Keywords: entorhinal cortex; timing; time; learning interval ... See more keywords
Entorhinal fast-spiking speed cells project to the hippocampus
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1720855115
Abstract: Significance Our location in space is represented by a spectrum of space and direction-responsive cell types in medial entorhinal cortex and hippocampus. Many cells in these areas respond also to running speed. The presence of… read more here.
Keywords: fast spiking; hippocampus; speed cells; speed ... See more keywords
Post‐Inhibitory Rebound Spikes in Rat Medial Entorhinal Layer II/III Principal Cells: In Vivo, In Vitro, and Computational Modeling Characterization
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DOI: 10.1093/cercor/bhw058
Abstract: Abstract Medial entorhinal cortex Layer‐II stellate cells (mEC‐LII‐SCs) primarily interact via inhibitory interneurons. This suggests the presence of alternative mechanisms other than excitatory synaptic inputs for triggering action potentials (APs) in stellate cells during spatial… read more here.
Keywords: lii scs; mec lii; post inhibitory; inhibitory ... See more keywords
Theta resonance and synaptic modulation scale activity patterns in the medial entorhinal cortex stellate cells
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14434
Abstract: Stellate cells (SCs) of the medial entorhinal cortex (MEC) are rich in hyperpolarization‐activated cyclic nucleotide–gated (HCN) channels, which are known to effectively shape their activity patterns. The explanatory mechanisms, however, have remained elusive. One important… read more here.
Keywords: modulation; entorhinal cortex; activity patterns; hcn channels ... See more keywords
Development of Parvalbumin-Expressing Basket Terminals in Layer II of the Rat Medial Entorhinal Cortex
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DOI: 10.1523/eneuro.0438-17.2018
Abstract: Visual Abstract Grid cells in layer II of the medial entorhinal cortex (MEC LII) generate multiple regular firing fields in response to the position and speed of an individual within the environment. They exhibit a… read more here.
Keywords: mec lii; medial entorhinal; entorhinal cortex; development ... See more keywords
Kinetics and Connectivity Properties of Parvalbumin- and Somatostatin-Positive Inhibition in Layer 2/3 Medial Entorhinal Cortex
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DOI: 10.1523/eneuro.0441-21.2022
Abstract: Abstract Parvalbumin-positive (Pvalb+) and somatostatin-positive (Sst+) cells are the two largest subgroups of inhibitory interneurons. Studies in visual cortex indicate that synaptic connections between Pvalb+ cells are common while connections between Sst+ interneurons have not… read more here.
Keywords: inhibition; entorhinal cortex; medial entorhinal; cortex ... See more keywords
Differential Contribution of Ca2+-Dependent Mechanisms to Hyperexcitability in Layer V Neurons of the Medial Entorhinal Cortex
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00182
Abstract: Temporal lobe epilepsy is characterized by recurrent seizures in one or both temporal lobes of the brain; some in vitro models show that epileptiform discharges initiate in entorhinal layer V neurons and then spread into… read more here.
Keywords: layer neurons; differential contribution; ca2; medial entorhinal ... See more keywords