Application of the median method to estimate the kinetic constants of the substrate uncompetitive inhibition equation.
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DOI: 10.1016/j.jtbi.2017.01.033
Abstract: In 1974, Eisenthal and Cornish-Bowden published the direct linear plot method, which used the median to estimate the Vmax and Km from a set of initial rates as a function of substrate concentrations. The robustness… read more here.
Keywords: method; uncompetitive inhibition; median method; equation ... See more keywords