Potential mechanism for hyperhomocysteinemia in Greyhound dogs
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Veterinary Internal Medicine"
DOI: 10.1111/jvim.16700
Abstract: Abstract Background Greyhounds have been reported to have hyperhomocysteinemia (HHC), but the underlying mechanisms and clinical implications are unclear. Hypothesis Our primary aim was to assess serum concentrations of homocysteine (HCy) and related analytes in… read more here.
Keywords: cobalamin; greyhounds median; serum; methionine ... See more keywords
Genetic polymorphism of CYP3A4 is associated with poor response to ifosfamide treatment in children with solid embryonic tumors
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Medical Science"
DOI: 10.5114/aoms.2019.86648
Abstract: The CYP450 complex participates in the metabolism of ifosfamide, an antineoplastic drug used to treat solid tumors. genes contain several single nucleotide polymorphisms (SNPs) that confer different activity towards the enzyme. The aim of our… read more here.
Keywords: response; median mol; q25 q75; patients genotype ... See more keywords