Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.12.048
Abstract: Abstract Glioblastoma multiforme (GBM) has few clinically approved therapeutic regimens. One of these therapeutic options includes placing biodegradable wafers releasing BCNU (Gliadel®) into the tumor bed at the time of surgical removal of the tumor.… read more here.
Keywords: wafers releasing; wafer; median survival; drug ... See more keywords
Estimation of median survival time and its 95% confidence interval using SAS PROC LIFETEST.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biopharmaceutical statistics"
DOI: 10.1080/10543406.2023.2206481
Abstract: Estimation of median survival and its 95% confidence interval depends on the choice of the survival function, standard error, and a method for constructing the confidence interval. This paper outlines several available possibilities in SAS®… read more here.
Keywords: median survival; log; confidence interval;
Short-term efficacy of cholecystectomy plus bile duct T-tube drainage or choledochojejunostomy in the treatment of gallbladder cancer and its effects on median survival time and postoperative complications
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000032689
Abstract: To explore the short-term efficacy of cholecystectomy plus bile duct T-tube drainage or choledochojejunostomy (CJ) in the treatment of gallbladder cancer (GC) and its effects on the median survival time and postoperative complications. The clinical… read more here.
Keywords: time; median survival; group; bile duct ... See more keywords
Clinical significance of TP53 mutations in adult T-cell leukemia/lymphoma.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of haematology"
DOI: 10.1111/bjh.17749
Abstract: Adult T-cell leukaemia/lymphoma (ATL) patients have a poor prognosis. Here, we investigated the impact of TP53 gene mutations on prognosis of ATL treated in different ways. Among 177 patients, we identified 47 single nucleotide variants… read more here.
Keywords: median survival; adult cell; mutations years; cell ... See more keywords
Should Myelodysplastic Syndromes in Very Old Patients be More Actively Managed? Clinical Characteristics, Management and Outcomes for Patients 85 Years and Older
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-113290
Abstract: Introduction Myelodysplastic Syndrome (MDS) is classically a disease of older people, with median age at presentation of 70-75 years. The incidence of MDS is estimated at 5-13/100,000/year, but rises to >20/100,000/year in older populations. An… read more here.
Keywords: diagnosis; median survival; management; old patients ... See more keywords
Prognostic Value of Initial Blood Cell Counts in Acute Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-133377
Abstract: Introduction: Acute myeloid leukemia (AML) is an aggressive hematologic malignancy that has a poor prognosis. Not only does AML lead to mortality, but toxicity from chemotherapy can result in life-threatening complications. While the goal of… read more here.
Keywords: myeloid leukemia; acute myeloid; blood; treatment ... See more keywords
LSC - 2017 - KRAS & TP53 mutations cause malignant mesothelioma
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.oa293
Abstract: Background: Malignant pleural mesothelioma (MPM) is a highly aggressive tumor linked to loss of tumor suppressorsBAP1, NF2, andTRP53and accompanied by malignant pleural effusion (MPE). Aim: To develop novel mouse models of MPM with MPE. Methods:… read more here.
Keywords: mpm; mesothelioma; median survival; lsc 2017 ... See more keywords
Survival of eight LLIN brands 6, 12, 24 and 36 months after a mass distribution campaign in rural and urban settings in Senegal
Sign Up to like & getrecommendations! Published in 2022 at "BMC Public Health"
DOI: 10.1186/s12889-022-13051-w
Abstract: Background Long lasting insecticidal nets (LLIN) are one of the core components of global malaria prevention and control. The lifespan of LLIN varies widely depending on the population or environment, and randomized studies are required… read more here.
Keywords: llin brands; time; permanet; rural urban ... See more keywords
Actionable tests and treatments for patients with gastrointestinal cancers and historically short median survival times
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0276492
Abstract: Background Patients have difficult unmet needs when standard chemotherapy produces a median survival of less than 1 year or many patients will experience severe toxicities. Blood tests can predict their survival. Methods Analyses evaluate predictive… read more here.
Keywords: blood tests; actionable tests; median survival; survival ... See more keywords
Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.633210
Abstract: Glioblastoma (GBM) is the most aggressive adult glioma with a median survival of 14 months. While standard treatments (safe maximal resection, radiation, and temozolomide chemotherapy) have increased the median survival in favorable O(6)-methylguanine-DNA methyltransferase (MGMT)-methylated… read more here.
Keywords: glioblastoma; median survival; fatty acid; rano ... See more keywords
Clinical Characteristics and Prognosis of Renal Cell Carcinoma With Spinal Bone Metastases
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.659779
Abstract: Background The prognosis of renal cell carcinoma (RCC) with spinal bone metastasis (sBM) varies greatly. In this study, we aimed to define the clinical characteristics and prognostic factors of RCC with spinal bone metastasis (sBM)… read more here.
Keywords: survival time; spinal bone; median survival; metastasis ... See more keywords