Articles with "mediated acquired" as a keyword



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EMT-Mediated Acquired EGFR-TKI Resistance in NSCLC: Mechanisms and Strategies

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Published in 2019 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2019.01044

Abstract: Acquired resistance inevitably limits the curative effects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), which represent the classical paradigm of molecular-targeted therapies in non-small-cell lung cancer (NSCLC). How to break such a bottleneck… read more here.

Keywords: tki resistance; resistance; emt mediated; mediated acquired ... See more keywords