Preparation of 2,4,5-Trisubstituted Oxazoles through Iodine-mediated Aerobic Oxidative Cyclization of Enaminones.
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DOI: 10.1021/acs.orglett.8b00376
Abstract: A novel approach to trisubstituted oxazoles has been developed that is based upon an iodine-mediated aerobic oxidative cyclization of enaminone derivatives. This transition-metal-free procedure was highly efficient and involved the removal of four hydrogen atoms… read more here.
Keywords: iodine mediated; aerobic oxidative; mediated aerobic; trisubstituted oxazoles ... See more keywords