T Cell Mediated Autoimmunity in Immune Thrombocytopenia.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of haematology"
DOI: 10.1111/ejh.13705
Abstract: Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a low platelet count and an increased risk of bleeding. In addition to anti-platelet autoantibodies, CD8+ T cells have been implicated as a mechanism of platelet… read more here.
Keywords: cell mediated; mediated autoimmunity; cd8 cells; immune thrombocytopenia ... See more keywords
Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci97333
Abstract: Uncontrolled secretion of type I IFN, as the result of endosomal TLR (i.e., TLR7 and TLR9) signaling in plasmacytoid DCs (pDCs), and abnormal production of autoantibodies by B cells are critical for systemic lupus erythematosus… read more here.
Keywords: murine; mediated autoimmunity; galectin inhibits; tlr7 mediated ... See more keywords
Activation of NLR-Mediated Autoimmunity in Arabidopsis Early in Short Days 4 Mutant
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.881212
Abstract: From a reverse genetic screen using CRISPR/Cas9 gene editing tool, we unintentionally identified an autoimmune mutant. Map-based cloning and whole-genome sequencing revealed that it contains a deletion in SMALL UBIQUITIN-RELATED MODIFIER (SUMO) protease encoding gene… read more here.
Keywords: mediated autoimmunity; early short; activation nlr; autoimmunity ... See more keywords