Metal-Organic Framework-Mediated Bioorthogonal Reaction to Immobilize Bacteria for Ultrasensitive Fluorescence Counting Immunoassays.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c21350
Abstract: Ultrasensitive quantification of protein biomarkers has significant implications in disease diagnosis. Herein, we report a fluorescent bacteria counting immunoassay (FBCIA) strategy for protein biomarker detection based on a cascade signal conversion and amplification strategy including… read more here.
Keywords: organic framework; metal organic; detection; mediated bioorthogonal ... See more keywords
An enzyme-mediated bioorthogonal labeling method for genome-wide mapping of 5-hydroxymethyluracil
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d1sc03812e
Abstract: DNA 5-hydroxymethyluracil (5hmU) is a thymine modification existing in the genomes of various organisms. The post-replicative formation of 5hmU occurs via hydroxylation of thymine by ten-eleven translocation (TET) dioxygenases in mammals and J-binding proteins (JBPs)… read more here.
Keywords: enzyme mediated; bioorthogonal labeling; labeling method; mediated bioorthogonal ... See more keywords