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   Articles with "mediated biotransformation" as a keyword



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New derivatives of the iridoid specioside from fungal biotransformation.

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recommendations! Published in 2021 at "Applied microbiology and biotechnology"

DOI: 10.1007/s00253-021-11504-7

Abstract: Iridoids are widely found from species of Bignoniaceae family and exhibit several biological activities, such as anti-inflammatory, antimicrobial, antioxidant, and antitumor. Specioside is an iridoid found from Tabebuia species, mainly in Tabebuia aurea. Thus, here… read more here.

Keywords: ester hydrolysis; glycosylated specioside; biotransformation; non glycosylated ... See more keywords
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Cordyceps sinensis-mediated biotransformation of notoginsenoside R1 into 25-OH-20(S/R)-R2 with elevated cardioprotective effect against DOX-induced cell injury

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recommendations! Published in 2022 at "RSC Advances"

DOI: 10.1039/d2ra01470j

Abstract: Notoginsenoside R1 is a dammarane saponin in Panax notoginseng with promising cardioprotective effects. The bioactivity–structure relationship of such saponins suggested that the presence of a hydroxyl group at C25 could elevate its performance. To fulfill… read more here.

Keywords: effect; mediated biotransformation; sinensis mediated; cordyceps sinensis ... See more keywords
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A new metabolite from Cunninghamella blakesleeana-mediated biotransformation of an oral contraceptive drug, levonorgestrel

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recommendations! Published in 2019 at "Natural Product Research"

DOI: 10.1080/14786419.2019.1655018

Abstract: Abstract Cunninghamella blakesleeana-mediated biotransformation of an oral contraceptive drug, levonorgestrel (1), yielded a new metabolite, 13β-ethyl-17α-ethynyl-10,17β-dihydroxy-4,6-dien-3-one (2), and two known metabolites 3 (13β-ethyl-17α-ethynyl-10β,17β-dihydroxy-4-en-3-one), and 4 (13β-ethyl-17α-ethynyl-6β,17β-dihydroxy-4-en-3-one) at an ambient temperature using aqueous media. Hydroxylation and… read more here.

Keywords: blakesleeana mediated; cunninghamella blakesleeana; new metabolite; biotransformation oral ... See more keywords