Immunoglobulin G complexes without sialic acids enhance osteoclastogenesis but do not affect arthritis‐mediated bone loss
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13009
Abstract: Immunoglobulin G (IgG) is important in clearance and recognition of previously presented antigens and after activation, IgGs can interact with the Fc gamma receptors (FcγRs) on haematopoietic cells, including bone‐resorbing osteoclasts. The pathogenicity of IgG,… read more here.
Keywords: arthritis mediated; bone loss; mediated bone; igg complexes ... See more keywords
Pristimerin Protects Against OVX-Mediated Bone Loss by Attenuating Osteoclast Formation and Activity via Inhibition of RANKL-Mediated Activation of NF-κB and ERK Signaling Pathways
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DOI: 10.2147/dddt.s283694
Abstract: Introduction Osteoporosis is an osteolytic bone condition characterized by decreased bone strength and increased bone fragility. It is the result of elevated formation or activity of bone-resorbing osteoclasts. Although current therapeutic agents are efficacious against… read more here.
Keywords: mediated bone; formation; activity; bone loss ... See more keywords