Regulation of NLRP3 inflammasome by CD38 through cADPR-mediated Ca2+ release in vascular smooth muscle cells in diabetic mice.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117758
Abstract: AIMS NLR family pyrin domain containing 3 (NLRP3) inflammasome activation contributes to the development of diabetic cardiovascular complications. CD38 regulates vascular inflammation through cyclic ADP-ribose (cADPR)-mediated Ca2+ signaling in vascular smooth muscle cells (VSMCs). Ca2+… read more here.
Keywords: cadpr mediated; inflammasome activation; cadpr; mediated ca2 ... See more keywords
Aging alters spontaneous and neurotransmitter‐mediated Ca2+ signaling in smooth muscle cells of mouse mesenteric arteries
Sign Up to like & getrecommendations! Published in 2020 at "Microcirculation"
DOI: 10.1111/micc.12607
Abstract: Aging impairs MA dilation by reducing the ability of sensory nerves to counteract sympathetic vasoconstriction. This study tested whether altered SMC Ca2+ signals to sympathetic (NE) and sensory (CGRP) neurotransmitters underlie aging‐related deficits in vasodilation. read more here.
Keywords: neurotransmitter mediated; spontaneous neurotransmitter; mediated ca2; aging alters ... See more keywords
Localized TPC1-mediated Ca2+ release from endolysosomes contributes to myoseptal junction development in zebrafish.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell science"
DOI: 10.1242/jcs.259564
Abstract: In the trunk of developing zebrafish embryos, adjacent myotome blocks transmit contractile force via myoseptal junctions (MJs), dynamic structures that connect the actin cytoskeleton of skeletal muscle cells to extracellular matrix components via transmembrane protein… read more here.
Keywords: ca2 release; mediated ca2; release endolysosomes; localized tpc1 ... See more keywords
RyR2-Mediated Ca2+ Release and Mitochondrial ROS Generation Partake in the Synaptic Dysfunction Caused by Amyloid β Peptide Oligomers
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2017.00115
Abstract: Amyloid β peptide oligomers (AβOs), toxic aggregates with pivotal roles in Alzheimer’s disease, trigger persistent and low magnitude Ca2+ signals in neurons. We reported previously that these Ca2+ signals, which arise from Ca2+ entry and… read more here.
Keywords: ca2 release; mediated ca2; fragmentation; mitochondrial ca2 ... See more keywords
Role of Calcium-Sensing Receptor in Mechanotransducer-Channel-Mediated Ca2+ Influx in Hair Cells of Zebrafish Larvae
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.00649
Abstract: The calcium-sensing receptor (CaSR) is an extracellular Ca2+ sensor that plays a critical role in maintaining Ca2+ homeostasis in several organs, including the parathyroid gland and kidneys. In this study, through in situ hybridization, the… read more here.
Keywords: hair cells; hair; mediated ca2; channel mediated ... See more keywords
TRPM7-Mediated Ca2+ Regulates Mussel Settlement through the CaMKKβ-AMPK-SGF1 Pathway
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065399
Abstract: Many marine invertebrates have planktonic larval and benthic juvenile/adult stages. When the planktonic larvae are fully developed, they must find a favorable site to settle and metamorphose into benthic juveniles. This transition from a planktonic… read more here.
Keywords: mediated ca2; trpm7 mediated; settlement; camkk ampk ... See more keywords