Association of Trauma With Long-Term Risk of Death and Immune-Mediated or Cancer Disease in Same-Sex Twins.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA surgery"
DOI: 10.1001/jamasurg.2023.1560
Abstract: Importance Immediate consequences of trauma include a rapid and immense activation of the immune system, whereas long-term outcomes include premature death, physical disability, and reduced workability. Objective To investigate if moderate to severe trauma is… read more here.
Keywords: twin; trauma; mediated cancer; immune mediated ... See more keywords
Biomaterials Facilitating Dendritic Cell-Mediated Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202301339
Abstract: Dendritic cell (DC)-based cancer immunotherapy has exhibited remarkable clinical prospects because DCs play a central role in initiating and regulating adaptive immune responses. However, the application of traditional DC-mediated immunotherapy is limited due to insufficient… read more here.
Keywords: immunotherapy; mediated cancer; dendritic cell; cancer ... See more keywords
Promising approaches of small interfering RNAs (siRNAs) mediated cancer gene therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.144071
Abstract: RNA interference (RNAi) has extensive potential to revolutionize every aspect of clinical application in biomedical research. One of the promising tools is the Small interfering RNA (siRNA) molecules within a cellular component. Principally, siRNA mediated… read more here.
Keywords: therapy; mediated cancer; small interfering; cancer gene ... See more keywords
Supramolecular Cyclic Dinucleotide Nanoparticles for STING-Mediated Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.2c12685
Abstract: Activation of stimulator of interferon genes (STING) can reprogram the immunosuppressive tumor microenvironment (TME) by initiating innate and adaptive immunity. As natural STING agonists, clinical translation of cyclic dinucleotides (CDNs) has been challenged by their… read more here.
Keywords: cdg; mediated cancer; cyclic dinucleotide; sting mediated ... See more keywords
An iron(iii) complex selectively mediated cancer cell death: crystal structure, DNA targeting and in vitro antitumor activities
Sign Up to like & getrecommendations! Published in 2019 at "Inorganic Chemistry Frontiers"
DOI: 10.1039/c9qi00030e
Abstract: Three new iron(iii) complexes were prepared, and complex 3 exhibited a 14-fold higher selectivity index for HeLa vs. LO2 normal cells than cisplatin. read more here.
Keywords: iii; selectively mediated; iron iii; mediated cancer ... See more keywords
ROS-Mediated Cancer Cell Killing through Dietary Phytochemicals
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/9051542
Abstract: Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations, activating oncogenes, and raising oxidative stress, which all influence cell proliferation, survival, and apoptosis. Cancer cells display redox imbalance due to increased ROS level compared… read more here.
Keywords: ros mediated; mediated cancer; dietary phytochemicals; cancer cells ... See more keywords
IFN-γ enhances the antitumor activity of attenuated salmonella-mediated cancer immunotherapy by increasing M1 macrophage and CD4 and CD8 T cell counts and decreasing neutrophil counts
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.996055
Abstract: Bacteria-mediated cancer immunotherapy (BCI) inhibits tumor progression and has a synergistic antitumor effect when combined with chemotherapy. The anti- or pro-tumorigenic effects of interferon-γ (IFN-γ) are controversial; hence, we were interested in the antitumor effects… read more here.
Keywords: mediated cancer; tumor; attenuated salmonella; cancer immunotherapy ... See more keywords
Onco-Pathogen Mediated Cancer Progression and Associated Signaling Pathways in Cancer Development
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens"
DOI: 10.3390/pathogens12060770
Abstract: Infection with viruses, bacteria, and parasites are thought to be the underlying cause of about 8–17% of the world’s cancer burden, i.e., approximately one in every five malignancies globally is caused by an infectious pathogen.… read more here.
Keywords: mediated cancer; progression; pathogen mediated; onco pathogen ... See more keywords