How Polycomb‐Mediated Cell Memory Deals With a Changing Environment
Sign Up to like & getrecommendations! Published in 2018 at "BioEssays"
DOI: 10.1002/bies.201700137
Abstract: Cells and tissues are continuously exposed to a changing microenvironment, hence the necessity of a flexible modulation of gene expression that in complex organism have been achieved through specialized chromatin mechanisms. Chromatin‐based cell memory enables… read more here.
Keywords: polycomb mediated; cell memory; mediated cell; cell ... See more keywords
Traction force-mediated B cell activation: how and why
Sign Up to like & getrecommendations! Published in 2019 at "Science China Life Sciences"
DOI: 10.1007/s11427-019-9533-7
Abstract: Department of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing 100871, China; MOE Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School… read more here.
Keywords: life sciences; force mediated; mediated cell; traction force ... See more keywords
Structural characterization of a pectin-type polysaccharide from Curcuma kwangsiensis and its effects on reversing MDSC-mediated T cell suppression.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.04.153
Abstract: Myeloid-derived suppressor cells (MDSCs) accumulate in tumor-bearing hosts and play a major role in tumor-induced immunosuppression. The potent modulatory effects of polysaccharides on the innate and adaptive immune system stimulate antitumor responses. In this study,… read more here.
Keywords: pectin type; mdsc mediated; mediated cell; mdsc ... See more keywords
Facile Click-Mediated Cell Imaging Strategy of Liposomal Azido Mannosamine Lipids via Metabolic or Nonmetabolic Glycoengineering
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DOI: 10.1021/acsomega.0c01644
Abstract: Two Ac4ManNAz (AAM) derivatives with octadecanoic ester (C18 ester) and octadecyl ether (C18 ether) attached to the anomeric hydroxyl groups were synthesized and used in preparation of liposomes. Both liposomes show strong cell-labeling efficiencies on… read more here.
Keywords: cell imaging; imaging strategy; facile click; mediated cell ... See more keywords
Structure–Activity Relationships of RGD-Containing Peptides in Integrin αvβ5-Mediated Cell Adhesion
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c06540
Abstract: The RGD motif is a cell adhesion sequence that binds to integrins, a receptor family for extracellular matrix proteins. We previously reported that the RGDX1X2 sequence, where X1X2 is VF or NY, is required for… read more here.
Keywords: adhesion; cell adhesion; containing peptides; mediated cell ... See more keywords
Mitochondrion-targeted selenium nanoparticles enhance reactive oxygen species-mediated cell death.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/c9nr09039h
Abstract: Selenium nanoparticles (SeNPs) can induce reactive oxygen species (ROS)-mediated cell death when accumulated in cancer cells, while rendering anti-oxidation and cancer prevention in healthy tissues at low doses. Although they are promising anticancer agents with… read more here.
Keywords: reactive oxygen; oxygen species; mediated cell; cancer ... See more keywords
Reduction in N-methyl-D-aspartate Receptor-mediated Cell Death in Hippocampal Neurons by Glucose Reduction Preconditioning
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurosurgical Anesthesiology"
DOI: 10.1097/ana.0000000000000431
Abstract: Background: Repeated episodes of reduced glucose availability can precondition the brain against damage caused by severe hypoglycemia. Because N-methyl-D-aspartate (NMDA) receptor activation may contribute to neuronal loss in the hippocampus following glucose deprivation, we tested… read more here.
Keywords: reduction; death; mediated cell; cell death ... See more keywords
ROS-mediated cell death and phase separation in gynecological malignancies
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Medical Research"
DOI: 10.1186/s40001-025-02846-3
Abstract: Reactive oxygen species (ROS) are reactive products of cellular metabolism that, under physiological conditions, activate specific signaling pathways essential for cellular functions. Excessive accumulation of ROS overwhelms cellular antioxidant defenses, leading to functional damage or… read more here.
Keywords: mediated cell; ros mediated; gynecological malignancies; cell ... See more keywords
Lipotoxicity Induces β-cell Small Extracellular Vesicle–Mediated β-cell Dysfunction in Male Mice
Sign Up to like & getrecommendations! Published in 2025 at "Endocrinology"
DOI: 10.1210/endocr/bqaf067
Abstract: Abstract Chronically elevated circulating excess free fatty acids (ie, lipotoxicity) is a pathological process implicated in several metabolic disorders, including obesity-driven type 2 diabetes (T2D). Lipotoxicity exerts detrimental effects on pancreatic islet β-cells by reducing… read more here.
Keywords: mediated cell; cell dysfunction; lipotoxicity; small extracellular ... See more keywords
AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cell science"
DOI: 10.1242/jcs.239277
Abstract: Oncogenes can create metabolic vulnerabilities in cancer cells. We tested how AKT and MYC affect the ability of cells to shift between respiration and glycolysis. Using immortalized mammary epithelial cells, we discovered that constitutively active… read more here.
Keywords: akt; death; mediated cell; akt myc ... See more keywords
Identification and Validation of Hub Genes Related to Neutrophil Extracellular Traps-Mediated Cell Damage During Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s444975
Abstract: Purpose Studies have shown that neutrophil-mediated formation of neutrophil extracellular traps (NETs) leads to increased inflammatory response and cellular tissue damage during myocardial infarction (MI). We aimed to identify and validate possible hub genes in… read more here.
Keywords: mediated cell; hub; damage; expression ... See more keywords