The PPARγ‐SETD8 axis constitutes an epigenetic, p53‐independent checkpoint on p21‐mediated cellular senescence
Sign Up to like & getrecommendations! Published in 2017 at "Aging Cell"
DOI: 10.1111/acel.12607
Abstract: Cellular senescence is a permanent proliferative arrest triggered by genome instability or aberrant growth stresses, acting as a protective or even tumor‐suppressive mechanism. While several key aspects of gene regulation have been known to program… read more here.
Keywords: mediated cellular; senescence; ppar setd8; cellular senescence ... See more keywords
Sleep inhibition induced by amyloid‐β oligomers is mediated by the cellular prion protein
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Sleep Research"
DOI: 10.1111/jsr.13187
Abstract: Sleep is severely impaired in patients with Alzheimer's disease. Amyloid‐β deposition in the brain of Alzheimer's disease patients is a key event in its pathogenesis and is associated with disrupted sleep, even before the appearance… read more here.
Keywords: amyloid oligomers; mediated cellular; prion protein; cellular prion ... See more keywords
Extracellular vesicle-mediated cellular crosstalk in lung repair, remodelling and regeneration
Sign Up to like & getrecommendations! Published in 2022 at "European Respiratory Review"
DOI: 10.1183/16000617.0106-2021
Abstract: The unperturbed lung is highly quiescent, with a remarkably low level of cell turnover. However, once damaged, the lung shows an extensive regenerative capacity, with resident progenitor cell populations re-entering the cell cycle and differentiating… read more here.
Keywords: regeneration; cell; mediated cellular; lung ... See more keywords
Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival
Sign Up to like & getrecommendations! Published in 2022 at "Oncotarget"
DOI: 10.18632/oncotarget.28277
Abstract: PARP10 is a mono-ADP-ribosyltransferase with multiple cellular functions, including proliferation, apoptosis, metabolism and DNA repair. PARP10 is overexpressed in a significant proportion of tumors, particularly breast and ovarian cancers. Identifying genetic susceptibilities based on PARP10… read more here.
Keywords: genome wide; mediated cellular; parp10; parp10 mediated ... See more keywords
Biosensors for Studies on Adhesion-Mediated Cellular Responses to Their Microenvironment
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.597950
Abstract: Cells interact with their microenvironment by constantly sensing mechanical and chemical cues converting them into biochemical signals. These processes allow cells to respond and adapt to changes in their environment, and are crucial for most… read more here.
Keywords: mediated cellular; biosensors studies; cellular responses; adhesion mediated ... See more keywords
Thermo-Priming Mediated Cellular Networks for Abiotic Stress Management in Plants
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.866409
Abstract: Plants can adapt to different environmental conditions and can survive even under very harsh conditions. They have developed elaborate networks of receptors and signaling components, which modulate their biochemistry and physiology by regulating the genetic… read more here.
Keywords: stress; mediated cellular; networks abiotic; priming mediated ... See more keywords