Articles with "mediated chondrocyte" as a keyword



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Electroacupuncture serum inhibits TNF-α-mediated chondrocyte inflammation via the Ras-Raf-MEK1/2-ERK1/2 signaling pathway

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Published in 2017 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2017.7366

Abstract: The Ras-Raf-mitogen-activated protein kinase kinase (MEK)1/2-extracellular signal-regulated kinase (ERK)1/2 signaling pathway contributes to the release of chondral matrix-degrading enzymes and accelerates the degradation of articular cartilage. Electroacupuncture (EA) treatment has been widely used for the… read more here.

Keywords: treatment; group; tnf mediated; signaling pathway ... See more keywords
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Oxidized low density lipoprotein facilitates tumor necrosis factor-α mediated chondrocyte death via autophagy pathway

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Published in 2017 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2017.7786

Abstract: We aimed to investigate the role of oxidized low density lipoprotein (ox-LDL) in tumor necrosis factor-α (TNF-α) mediated chondrocyte death and explore the mechanisms. Ten osteoarthritis (OA) and normal control cartilage tissue and synovial fluid… read more here.

Keywords: oxidized low; chondrocyte death; death; density lipoprotein ... See more keywords