Aligner-mediated cleavage-triggered exponential amplification for sensitive detection of nucleic acids.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2018.03.067
Abstract: Exponential amplification reaction (EXPAR), as a simple and high sensitive method, holds great promise in nucleic acids detection. One major challenge in EXPAR is the generation of trigger DNA with a definite 3'-end, which now… read more here.
Keywords: detection; exponential amplification; nucleic acids; mediated cleavage ... See more keywords
Specific and Reversible Enrichment of Early-Stage Glycated Proteome Based on Thiazolidine Chemistry and Palladium-Mediated Cleavage.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03648
Abstract: Comprehensive analysis of protein glycation is important for better understanding of its formation mechanism and biological significance. The current preconcentration methods of glycated proteome mainly depend on the reversible combination of boronic acid and cis-dihydroxy… read more here.
Keywords: glycated proteome; chemistry; thiazolidine chemistry; mediated cleavage ... See more keywords
HAT Catalysts to Facilitate Acid Mediated Cleavage of Biaryl C-C Bonds in Binaphthols.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03325
Abstract: A method to cleave the C-C biaryl bond of binaphthyl derivatives under reductive conditions is described. Triflic acid employed together with a catalytic HAT reagent, 2-ethyl-9,10-dihydroxyanthracene, that is regenerated using H2 with catalytic Pd/C yielded… read more here.
Keywords: cleavage biaryl; facilitate acid; catalysts facilitate; acid mediated ... See more keywords
Presenilin-mediated cleavage of APP regulates synaptotagmin-7 and presynaptic plasticity
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06813-x
Abstract: Mutations of the intramembrane protease presenilin (PS) or of its main substrate, the amyloid precursor protein (APP), cause early-onset form of Alzheimer disease. PS and APP interact with proteins of the neurotransmitter release machinery without… read more here.
Keywords: cleavage app; mediated cleavage; presenilin mediated; app ... See more keywords
Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B
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DOI: 10.1080/15548627.2016.1265192
Abstract: ABSTRACT The endoplasmic reticulum (ER) is exploited by several diverse viruses during their infectious life cycles. Flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), utilize the ER as a source of membranes to establish… read more here.
Keywords: cleavage fam134b; mediated cleavage; zikv; reticulophagy ... See more keywords
DFT Studies on Ni-Mediated C–F Cleavage for the Synthesis of Cyclopentadiene Derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2018.00319
Abstract: Density functional theory calculations have been performed to study the detailed mechanism of Ni-mediated [3+2] cycloaddition of 2-trifluoromethyl-1-alkenes with alkynes via cleavage of two C-F bonds. It was found that the reaction pathway involves oxidative… read more here.
Keywords: studies mediated; dft studies; mediated cleavage; cleavage ... See more keywords