Bullous pemphigoid autoantibody‐mediated complement fixation is abolished by the low‐molecular‐weight heparin tinzaparin sodium
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Dermatology"
DOI: 10.1111/bjd.18156
Abstract: bullous pemphigoid (BP) is an autoimmune blistering skin disease that predominantly occurs in the elderly, often accompanied by neurological disorders and increased mortality. Diagnosis of BP is established by clinical presentation, typical histology with subepidermal… read more here.
Keywords: microscopy; bullous pemphigoid; mediated complement; autoantibody mediated ... See more keywords
Troxerutin-Mediated Complement Pathway Inhibition is a Disease-Modifying Treatment for Inflammatory Arthritis
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DOI: 10.3389/fcell.2022.845457
Abstract: Troxerutin (TXR) is a phytochemical reported to possess anti-inflammatory and hepatoprotective effects. In this study, we aimed to exploit the antiarthritic properties of TXR using an adjuvant-induced arthritic (AIA) rat model. AIA-induced rats showed the… read more here.
Keywords: disease; troxerutin mediated; mediated complement; complement pathway ... See more keywords
Factors affecting IgG4-mediated complement activation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1087532
Abstract: Of the four human immunoglobulin G (IgG) subclasses, IgG4 is considered the least inflammatory, in part because it poorly activates the complement system. Regardless, in IgG4 related disease (IgG4-RD) and in autoimmune disorders with high… read more here.
Keywords: complement activation; igg4; igg4 mediated; mediated complement ... See more keywords