Resveratrol noncompetitively inhibits glycine receptor-mediated currents in neurons of rat central auditory neurons
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.12.021
Abstract: Resveratrol, a naturally occurring stilbene found in red wine, is known to modulate the activity of several types of ion channels and membrane receptors, including Ca2+, K+, and Na+ ion channels. However, little is known… read more here.
Keywords: mediated currents; glycine receptor; currents neurons; receptor ... See more keywords
Glutamate/GABA co-release selectively influences postsynaptic glutamate receptors in mouse cortical neurons
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2019.107737
Abstract: Cultured rat cortical neurons co-expressing VGLUT1 and VGAT (mixed synapses) co-release Glu and GABA. Here, mixed synapses were studied in cultured mouse cortical neurons to verify whether in mice mixed synapses co-release Glu and GABA,… read more here.
Keywords: mouse cortical; influences postsynaptic; mediated currents; mixed synapses ... See more keywords
Enhancement of P2X3 Receptor-Mediated Currents by Lysophosphatidic Acid in Rat Primary Sensory Neurons
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.928647
Abstract: Lysophosphatidic acid (LPA), a lipid metabolite, plays a role in both neuropathic and inflammatory pain through LPA1 receptors. P2X3 receptor has also been shown to participate in these pathological processes. However, it is still unclear… read more here.
Keywords: mediated currents; receptor mediated; lysophosphatidic acid; enhancement p2x3 ... See more keywords
Palmitoylation regulates the magnitude of HCN4-mediated currents in mammalian cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1163339
Abstract: The sinoatrial node (SAN) and subsidiary pacemakers in the cardiac conduction system generate spontaneous electrical activity which is indispensable for electrical and therefore contractile function of the heart. The hyperpolarisation-activated cyclic nucleotide-gated channel HCN4 is… read more here.
Keywords: mediated currents; hcn4 mediated; magnitude hcn4; amino terminus ... See more keywords
Molecular and Regulatory Mechanisms of Desensitization and Resensitization of GABAA Receptors with a Special Reference to Propofol/Barbiturate
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DOI: 10.3390/ijms21020563
Abstract: It is known that desensitization of GABAA receptor (GABAAR)-mediated currents is paradoxically correlated with the slowdown of their deactivation, i.e., resensitization. It has been shown that an upregulation of calcineurin enhances the desensitization of GABAAR-mediated… read more here.
Keywords: mediated currents; gabaar mediated; desensitization resensitization; desensitization ... See more keywords