Computational Study of Key Mechanistic Details for a Proposed Copper (I)-Mediated Deconstructive Fluorination of N-Protected Cyclic Amines
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DOI: 10.1007/s11244-021-01443-y
Abstract: Using calculations, we show that a proposed Cu(I)-mediated deconstructive fluorination of N -benzoylated cyclic amines with Selectfluor ® is feasible and may proceed through: (a) substrate coordination to a Cu(I) salt, (b) iminium ion formation… read more here.
Keywords: mediated deconstructive; deconstructive fluorination; iminium ion; fluorination ... See more keywords
PCET-mediated deconstructive cross-coupling of aliphatic alcohols
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DOI: 10.1039/d5sc00737b
Abstract: A practical deconstructive arylation of aliphatic alcohols has been developed using a synergistic photoredox proton-coupled electron transfer (PCET) and nickel dual catalytic system. The method efficiently generates alkyl radicals via concerted PCET-mediated β-scission, enabling the… read more here.
Keywords: mediated deconstructive; deconstructive cross; cross coupling; aliphatic alcohols ... See more keywords