Integrated Nanorod-Mediated PD-L1 Downregulation in Combination with Oxidative-Stress Immunogene Therapy Against Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300110
Abstract: It is an engaging program for tumor treatment that rationalizes the specific microenvironments, activation of suppressed immune system (immune resistance/escape reversion), and synergistic target therapy. Herein, a biomimetic nanoplatform that combines oxidative stress with genetic… read more here.
Keywords: stress; oxidative stress; therapy; nanorod mediated ... See more keywords
Relative contribution of molecular mechanisms to cumulative ligand-mediated downregulation of GRα.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2022.02.102
Abstract: Central to the pharmacological use of glucocorticoids (GCs) is the availability of the glucocorticoid receptor alpha (GRα). However, chronic GC therapy often results in the ligand-mediated downregulation of the GRα, and the subsequent development of… read more here.
Keywords: mediated downregulation; relative contribution; contribution molecular; molecular mechanisms ... See more keywords
lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma.
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DOI: 10.18632/aging.204756
Abstract: Integrin alpha L (ITGAL) seemed to play a critical role in carcinogenesis and immune regulation. Nevertheless, the effects of ITGAL on non-small cell lung cancer (NSCLC) remain elusive. The present paper intended to determine the… read more here.
Keywords: signaling pathway; lung adenocarcinoma; biomarker; lung ... See more keywords
miRNA mediated downregulation of cyclase-associated protein 1 (CAP1) is required for myoblast fusion
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DOI: 10.3389/fcell.2022.899917
Abstract: Myoblast fusion is essential for the formation, growth, and regeneration of skeletal muscle, but the molecular mechanisms that govern fusion and myofiber formation remain poorly understood. Past studies have shown an important role of the… read more here.
Keywords: fusion; cyclase associated; cap1; myoblast fusion ... See more keywords