Articles with "mediated drp1" as a keyword



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FK866 alleviates cerebral pyroptosis and inflammation mediated by Drp1 in a rat cardiopulmonary resuscitation model.

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Published in 2020 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2020.107032

Abstract: OBJECTIVES Dynamin-related protein 1 (Drp1) mediates mitochondrial fission and triggers NLRP3 inflammasome activation. FK866 (a NAMPT inhibitor) exerts a neuroprotective effect in ischemia/reperfusion injury through the suppression of mitochondrial dysfunction. We explored the effects of… read more here.

Keywords: pyroptosis inflammation; inflammation mediated; fk866; mediated drp1 ... See more keywords