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Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.05.040
Abstract: Large-scale transcriptomic profiling of glioblastoma (GBM) into subtypes has provided remarkable insight into the pathobiology and heterogeneous nature of this disease. The mechanisms of speciation and inter-subtype transitions of these molecular subtypes require better characterization to…
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Keywords:
like cells;
stem like;
mediated dynamic;
glioblastoma stem ... See more keywords
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Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.04.018
Abstract: Abstract A highly diastereoselective chloride-mediated dynamic kinetic resolution at phosphorus has been developed to access a key intermediate in the synthesis of GSK2248761A. This procedure utilises a soluble chloride source and a cheap readily available…
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Keywords:
chloride mediated;
diastereoselective chloride;
dynamic kinetic;
mediated dynamic ... See more keywords
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Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06452e
Abstract: Dynamic systems of cyclodextrins (CDs) enabled by a native cyclodextrin glucanotransferase (CGTase) can incorporate unnatural glucopyranose-derived building blocks, expanding the applicability of enzyme-mediated dynamic combinatorial chemistry by using synthetically modified substrates. Starting dynamic combinatorial libraries…
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Keywords:
unnatural cyclodextrins;
dynamic combinatorial;
combinatorial libraries;
mediated dynamic ... See more keywords