Articles with "mediated dynamic" as a keyword



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MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells.

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Published in 2017 at "Cell reports"

DOI: 10.1016/j.celrep.2017.05.040

Abstract: Large-scale transcriptomic profiling of glioblastoma (GBM) into subtypes has provided remarkable insight into the pathobiology and heterogeneous nature of this disease. The mechanisms of speciation and inter-subtype transitions of these molecular subtypes require better characterization to… read more here.

Keywords: like cells; stem like; mediated dynamic; glioblastoma stem ... See more keywords
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A highly diastereoselective chloride-mediated dynamic kinetic resolution at phosphorus on-route to a key intermediate in the synthesis of GSK2248761A

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Published in 2018 at "Tetrahedron Letters"

DOI: 10.1016/j.tetlet.2018.04.018

Abstract: Abstract A highly diastereoselective chloride-mediated dynamic kinetic resolution at phosphorus has been developed to access a key intermediate in the synthesis of GSK2248761A. This procedure utilises a soluble chloride source and a cheap readily available… read more here.

Keywords: chloride mediated; diastereoselective chloride; dynamic kinetic; mediated dynamic ... See more keywords
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Unnatural cyclodextrins can be accessed from enzyme-mediated dynamic combinatorial libraries.

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Published in 2022 at "Chemical communications"

DOI: 10.1039/d1cc06452e

Abstract: Dynamic systems of cyclodextrins (CDs) enabled by a native cyclodextrin glucanotransferase (CGTase) can incorporate unnatural glucopyranose-derived building blocks, expanding the applicability of enzyme-mediated dynamic combinatorial chemistry by using synthetically modified substrates. Starting dynamic combinatorial libraries… read more here.

Keywords: unnatural cyclodextrins; dynamic combinatorial; combinatorial libraries; mediated dynamic ... See more keywords