Upconversion nanoparticles as intracellular pH messengers
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-02768-5
Abstract: Upconversion nanoparticles (UCNPs) should be particularly well suited for measurement inside cells because they can be imaged down to submicrometer dimensions in near real time using fluorescence microscopy, and they overcome problems, such as photobleaching,… read more here.
Keywords: upconversion nanoparticles; nanoparticles intracellular; mediated endocytosis; ucnp phab ... See more keywords
Involvement of adaptor proteins in clathrin-mediated endocytosis of virus entry.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2021.105278
Abstract: The first step in the initiation of effective viral infection is breaking through the cytomembrane to enter the cell. Clathrin-mediated endocytosis is a key vesicular trafficking process in which a variety of cargo molecules are… read more here.
Keywords: clathrin mediated; mediated endocytosis; adaptor proteins; involvement adaptor ... See more keywords
Selective Intracellular Delivery of Ganglioside GM3-Binding Peptide through Caveolae/Raft-Mediated Endocytosis.
Sign Up to like & getrecommendations! Published in 2017 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.6b01262
Abstract: Glycosphingolipids are major components of the membrane raft, and several kinds of viruses and bacterial toxins are known to bind to glycosphingolipids in the membrane raft. Since the viral genes and pathogenic proteins that are… read more here.
Keywords: raft; raft mediated; delivery; mediated endocytosis ... See more keywords
Discrimination of Receptor-Mediated Endocytosis by Surface-Enhanced Raman Scattering
Sign Up to like & getrecommendations! Published in 2022 at "Langmuir"
DOI: 10.1021/acs.langmuir.1c03305
Abstract: Cellular energy required for the maintenance of cellular life is stored in the form of adenosine triphosphate (ATP). Understanding cellular mechanisms, including ATP-dependent metabolisms, is crucial for disease diagnosis and treatment, including drug development and… read more here.
Keywords: receptor mediated; surface enhanced; endocytosis; enhanced raman ... See more keywords
Mechanisms of clathrin-mediated endocytosis
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/nrm.2017.132
Abstract: Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide range of cargo molecules from the cell surface to the interior. Clathrin-mediated endocytosis was first described over 5 decades ago. Since its… read more here.
Keywords: clathrin mediated; mediated endocytosis; biology; mechanisms clathrin ... See more keywords
A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating
Sign Up to like & getrecommendations! Published in 2018 at "Cell Discovery"
DOI: 10.1038/s41421-018-0067-5
Abstract: Kif5b-driven anterograde transport and clathrin-mediated endocytosis (CME) are responsible for opposite intracellular trafficking, contributing to plasma membrane homeostasis. However, whether and how the two trafficking processes coordinate remain unclear. Here, we show that Kif5b directly… read more here.
Keywords: new role; large clathrin; clathrin coated; mediated endocytosis ... See more keywords
Membrane capacitance recordings resolve dynamics and complexity of receptor-mediated endocytosis in Wnt signalling
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-49082-4
Abstract: Receptor-mediated endocytosis is an essential process in signalling pathways for activation of intracellular signalling cascades. One example is the Wnt signalling pathway that seems to depend on endocytosis of the ligand-receptor complex for initiation of… read more here.
Keywords: capacitance recordings; endocytosis; mediated endocytosis; wnt signalling ... See more keywords
Integrating protein copy numbers with interaction networks to quantify stoichiometry in clathrin-mediated endocytosis
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-09259-w
Abstract: Proteins that drive processes like clathrin-mediated endocytosis (CME) are expressed at copy numbers within a cell and across cell types varying from hundreds (e.g. auxilin) to millions (e.g. clathrin). These variations contain important information about… read more here.
Keywords: clathrin mediated; clathrin; copy numbers; network ... See more keywords
The morphological role of ligand inhibitors in blocking receptor- and clathrin-mediated endocytosis.
Sign Up to like & getrecommendations! Published in 2022 at "Soft matter"
DOI: 10.1039/d1sm01710a
Abstract: Cells often internalize particles through endocytic pathways that involve the binding between cell receptors and particle ligands, which drives the cell membrane to wrap the particle into a delivery vesicle. Previous findings showed that receptor-mediated… read more here.
Keywords: inhibitors blocking; role ligand; morphological role; ligand inhibitors ... See more keywords
The influence of nanoparticle shape on clathrin-mediated endocytosis by computational study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Materials Chemistry B"
DOI: 10.1039/d3tb00322a
Abstract: Nanoparticles have been widely used in biomedical applications, such as gene/drug. Among physicochemical properties, shape is a vital design parameter for tuning cell uptake of nanoparticles. However, the regulatory mechanism... read more here.
Keywords: nanoparticle shape; endocytosis computational; clathrin mediated; shape clathrin ... See more keywords
Early and nonredundant functions of dynamin isoforms in clathrin-mediated endocytosis
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e20-06-0363
Abstract: Dynamin GTPases (Dyn1 and Dyn2) are indispensable proteins of the core clathrin-mediated endocytosis (CME) machinery. Best known for their role in fission at the late stages of CME, many studies have suggested that dynamin also… read more here.
Keywords: mediated endocytosis; clathrin mediated; stages cme; dynamin isoforms ... See more keywords