IL‐17A‐mediated ERK1/2/p65 signaling pathway is associated with cell apoptosis after non‐alcoholic steatohepatitis
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DOI: 10.1002/iub.1960
Abstract: Interleukin (IL)‐17A is pro‐inflammatory cytokine which has been identified as a noninvasive marker of the pathogenesis of non‐alcoholic steatohepatitis (NASH). However, the underlying role of IL‐17A in NASH progression remains unclear. This study was designed… read more here.
Keywords: apoptosis; erk1 p65; signaling pathway; mediated erk1 ... See more keywords
Leptomycin B attenuates neuronal death via PKA- and PP2B-mediated ERK1/2 activation in the rat hippocampus following status epilepticus
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DOI: 10.1016/j.brainres.2017.06.002
Abstract: Leptomycin B (LMB), originally developed as an anti-fungal agent, has potent neuroprotective properties against status epilepticus (SE, a prolonged seizure activity). However, the pharmacological profiles and mechanisms of LMB for neuroprotection remain elusive. In the… read more here.
Keywords: lmb; mediated erk1; neuronal death; pka pp2b ... See more keywords