Articles with "mediated ferritinophagy" as a keyword



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Nuclear receptor coactivator 4-mediated ferritinophagy drives proliferation of dental pulp stem cells in hypoxia.

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Published in 2021 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2021.03.075

Abstract: Nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy has been implicated in the ferroptosis in cancer cells and hematopoiesis in the bone marrow. However, the role of iron metabolism, especially NCOA4-mediated degradation of ferritin, has not been… read more here.

Keywords: hypoxia; proliferation; mediated ferritinophagy; receptor ... See more keywords
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Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy

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Published in 2023 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2023.2189908

Abstract: Abstract Context Schisandrin B (Sch B), an active ingredient from Schisandrae chinensis (Turcz.) Baill. (Schisandraceae) Fructus, possesses diverse pharmacological activities including antitumor, anti-inflammation, and hepatoprotection. Objective To explore the effect of Sch B on activated… read more here.

Keywords: hscs senescence; sch; mediated ferritinophagy; senescence ... See more keywords
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NCOA4-Mediated Ferritinophagy Is Essential for HT22 Neuronal Cell Survival During Iron Deficiency (OR15-07-19).

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Published in 2019 at "Current developments in nutrition"

DOI: 10.1093/cdn/nzz044.or15-07-19

Abstract: Objectives Iron is essential for proper cell function and development. However, mishandled iron may lead to ferroptotic cell death. NCOA4 manages the cellular labile iron pool by controlling the release of ferritin iron via ferritinophagy.… read more here.

Keywords: iron deficiency; cell; ncoa4 mediated; mediated ferritinophagy ... See more keywords