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Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.814144
Abstract: The Polycomb Repressive Complex 2 (PRC2) plays important roles in the epigenetic regulation of cellular development and differentiation through H3K27me3-dependent transcriptional repression. Aberrant PRC2 activity has been associated with cancer and neurodevelopmental disorders, particularly with…
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Keywords:
mediated h3k27me3;
ezh2;
neuronal differentiation;
h3k27me3 targets ... See more keywords