Articles with "mediated hydroarylation" as a keyword



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2,2,2-Trifluoroethanol-mediated hydroarylation of fluorinated alkynes with indoles: Application to diindolylmethanes.

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Published in 2022 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202100488

Abstract: A new mild and practically simple alkyne hydroarylation protocol for the synthesis of 3-(indol-3-yl)-3-(trifluoromethyl)acrylic acid esters by the reaction of indole derivatives with ethyl/methyl 4,4,4-trifluoro-3-(indol-3-yl)but-2-enoates in trifluoroethanol was developed. This method has the following advantages:… read more here.

Keywords: alkynes indoles; trifluoroethanol mediated; hydroarylation fluorinated; mediated hydroarylation ... See more keywords